Results 31 to 40 of about 130,771 (285)

A hypoxia risk score for prognosis prediction and tumor microenvironment in adrenocortical carcinoma

open access: yesFrontiers in Genetics, 2022
Background: Adrenocortical carcinoma (ACC) is a rare malignant endocrine tumor derived from the adrenal cortex. Because of its highly aggressive nature, the prognosis of patients with adrenocortical carcinoma is not impressive. Hypoxia exists in the vast
Yuanyuan Deng   +7 more
doaj   +1 more source

GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo [PDF]

open access: yes, 2015
We have previously demonstrated that estrogen receptor (ER) alpha (ESR1) increases proliferation of adrenocortical carcinoma (ACC) through both an estrogen-dependent and -independent (induced by IGF-II/IGF1R pathways) manner.
Amendola, Donatella   +16 more
core   +2 more sources

Diagnosis and Treatment of Adrenocortical Oncocytoma: Case Report of Five Cases and Review of the Literature

open access: yesFrontiers in Oncology, 2019
Objective: To investigate the diagnosis and treatment of adrenocortical oncocytoma, and have a literature of review.Materials and Methods: The clinical data of 5 cases of adrenocortical oncocytoma treated in our hospital was retrospectively analyzed. The
Dexin Dong   +3 more
doaj   +1 more source

Adrenocortical carcinoma with inferior vena cava tumor thrombus found during surgery

open access: yesIJU Case Reports, 2022
Introduction The safety and efficacy of minimally invasive approaches for adrenocortical carcinoma with inferior vena cava tumor thrombus have not yet been established.
Yuta Nabeshima   +9 more
doaj   +1 more source

Methodological considerations in the analysis of fecal glucocorticoid metabolites in tufted capuchins (Cebus apella) [PDF]

open access: yes, 2013
Analysis of fecal glucocorticoid (GC) metabolites has recently become the standard method to monitor adrenocortical activity in primates noninvasively. However, given variation in the production, metabolism, and excretion of GCs across species and even ...
A Engelhardt   +66 more
core   +2 more sources

Gene Expression and Regulation in Adrenocortical Tumorigenesis

open access: yesBiology, 2012
Adrenocortical tumors are frequently found in the general population, and may be benign adrenocortical adenomas or malignant adrenocortical carcinomas. Unfortunately the clinical, biochemical and histopathological distinction between benign and malignant
Tobias Carling   +4 more
doaj   +1 more source

Estrogen-secreting adrenocortical carcinoma [PDF]

open access: yesYeungnam University Journal of Medicine, 2019
Adrenocortical carcinoma is a rare type of endocrine malignancy with an annual incidence of approximately 1–2 cases per million. The majority of these tumors secrete cortisol, and a few secrete aldosterone or androgen.
You Jeong   +6 more
doaj   +1 more source

Development of catecholamine and cortisol stress responses in zebrafish. [PDF]

open access: yes, 2014
Both adrenal catecholamines and steroids are known to be involved in the stress response, immune function, blood pressure and energy homeostasis. The response to stress is characterized by the activation of the hypothalamus-pituitary-adrenal (HPA) axis ...
Dipple, Katrina M   +4 more
core   +2 more sources

The Cut-downing Effect of Vitamin C on Erythrocyte Sedimentation Rate and Adrenocortical Effects of Etomidate in Patients Undergoing Laparotomy Surgery: A Randomized Clinical Trial

open access: yesJournal of Applied Hematology
OBJECTIVE: Suppression of the adrenocortical axis is the most disreputable side effect in patients who undergo mechanical ventilation and continuously sedated with etomidate.
Mahmood Khosravi   +7 more
doaj   +1 more source

Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance The currently used treatment regimen for the cancers of the adrenal cortex involves mitotane, a nonspecific derivative of the pesticide DDT (1,1-(dichlorobiphenyl)-2,2-dichloroethane), which has an unclear mechanism of action. Our studies in
A. Belavgeni   +16 more
semanticscholar   +1 more source

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