Results 41 to 50 of about 1,396,034 (289)

Adrenocortical Carcinoma

Menon G, Prasath S, Correa R.
europepmc   +3 more sources

New directions for the treatment of adrenal insufficiency [PDF]

, 2015
The following funding bodies supported this work: Biotechnology and Biological Sciences Research Council (BBSRC BB/L00267/1, to LG), Rosetrees Trust (to LG), Barts and The London Charity (417/2235, to LG), EU COFUND (PCOFUND-GA-2013-608765, to LG and GRB)
Allen, Allende, Badylak, Bancos, Berkes, Birke, Buaas, Chamoux, Chamoux, Clipsham, Cogger, Cox, Crawford, Drucker, Dubernard, El-Khairi, Else, Faulk, Fayard, Franksson, Freedman, Gallo-Payet, Gondo, Gondo, Grodstein, Guasti, Guasti, Hardy, Hardy, Hardy, Hardy, Hatano, Huang, Huang, Ibbertson, Jadhav, Kearns, Kim, King, Laufer, Ludwig, Luo, Mazilu, Parker, Sancho-Martinez, Schimmer, Schnabel, Sonoyama, Takahashi, Tanaka, Teebken, Thomas, Thomas, Thomas, Thomas, Thomas, Val, Val, Vierbuchen, Vouillarmet, Walczak, Walczak, Wei, Wilhelm, Wong, Yazawa, Yazawa, Yazawa, Yazawa, Zupekan   +69 more
core   +2 more sources

MicroRNAs as potential biomarkers in adrenocortical cancer: progress and challenges

Frontiers in Endocrinology, 2016
Adrenocortical carcinoma is a rare malignancy with poor prognosis and limited therapeutic options. Over the last decade, pan-genomic analyses of genetic and epigenetic alterations and genome-wide expression profile studies allowed major advances in the ...
Nadia eCHERRADI, Nadia eCHERRADI, Nadia eCHERRADI   +2 more
doaj   +1 more source

Case Report: Adrenocortical carcinoma in children—symptoms, diagnosis, and treatment

Frontiers in Endocrinology, 2023
Adrenocortical carcinomas are extremely rare in the paediatric population. Most of them are hormone-secretive lesions; therefore, they should be taken into consideration in a child with signs of precocious puberty and/or Cushing’s syndrome symptoms ...
Estera Zagojska, Magdalena Malka, Adrianna Gorecka, Iwona Ben-Skowronek   +3 more
doaj   +1 more source

Physiopathological Implications of 7TM Receptors [PDF]

, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +1 more source

Objective response and prolonged disease control of advanced adrenocortical carcinoma with cabozantinib.

Journal of Clinical Endocrinology and Metabolism, 2020
BACKGROUND Objective response of advanced adrenocortical carcinoma (ACC) to mitotane and cytotoxic chemotherapy regimen is only ~20% and early tumor progression is frequent.
M. Kroiss, Felix Megerle, Max Kurlbaum, S. Zimmermann, J. Wendler, C. Jimenez, C. Lapa, M. Quinkler, Oliver Scherf-Clavel, M. Habra, M. Fassnacht   +10 more
semanticscholar   +1 more source

Role of Scaffold Protein Proline-, Glutamic Acid-, and Leucine-Rich Protein 1 (PELP1) in the Modulation of Adrenocortical Cancer Cell Growth [PDF]

, 2017
PELP1 acts as an estrogen receptor (ER) coactivator that exerts an essential role in the ER's functions. ER coregulators have a critical role in the progression and response to hormonal treatment of estrogen-dependent tumors.
Avena, Paola, Casaburi, Ivan, Chimento, Adele, De Luca, Arianna, Fallo, Francesco, Pezzi, Vincenzo, Pilon, Catia, Sirianni, Rosa   +7 more
core   +2 more sources

Pharmacological profile and effects of mitotane in adrenocortical carcinoma

British Journal of Clinical Pharmacology, 2020
Mitotane is the only adrenolytic drug approved by the Food and Drug Administration for treating adrenocortical carcinoma (ACC). This drug has cytotoxic effects on tumour tissues; it induces cell death and antisecretory effects on adrenal cells by ...
C. Corso, A. Acco, C. Bach, S. Bonatto, B. C. de Figueiredo, L. D. de Souza   +5 more
semanticscholar   +1 more source

18F-FDG PET/CT image findings of a dog with adrenocortical carcinoma

BMC Veterinary Research, 2022
Background In human medicine, 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) has been used to differentiate between benign and malignant adrenal tumors and to identify metastases.
Dohee Lee, Taesik Yun, Yoonhoi Koo, Yeon Chae, Dongwoo Chang, Mhan-Pyo Yang, Byeong-Teck Kang, Hakhyun Kim   +7 more
doaj   +1 more source

Ectopic adrenocortical adenoma in the renal hilum mimicking a renal cell carcinoma

Radiology Case Reports, 2022
Ectopic adrenocortical tissue can arise along the path of embryonic migration, such as the celiac axis, broad ligament, adnexa of the testis, and spermatic cord.
Masashi Endo, MD, Hiroyuki Fujii, MD, PhD, Akifumi Fujita, MD, PhD, Tatsuya Takayama, MD, PhD, Daisuke Matsubara, MD, PhD, Tomohiro Kikuchi, MD, Saki Manaka, MD, Harushi Mori, MD, PhD   +7 more
doaj   +1 more source