Results 11 to 20 of about 921 (129)

Immunohistochemical expression of CYP11A1, CYP11B, CYP17, and HSD3B2 in functional and nonfunctional canine adrenocortical tumors. [PDF]

J Vet Intern Med
Abstract Background Functionality of human adrenal tumors is inferred by CYP11B1 (cortisol synthase) expression, CYP11B2 (aldosterone synthase) expression, or both. Hypothesis/Objectives Nonfunctional canine adrenal tumors have low expression of steroidogenic enzymes, whereas aldosterone‐producing tumors express CYP11B, and cortisol‐producing tumors ...
Allan F, Watson AH, Syme HM.
europepmc   +2 more sources

Lived experience of people with adrenocortical carcinoma and associated adrenal insufficiency

Endocrinology, Diabetes &Metabolism, Volume 5, Issue 4, July 2022., 2022
ACC appears to have high impact on lived experience of patients including their wellbeing and AI management. Further qualitative study is needed to understand the interactions of these two conditions, it's influences on patients' journey and survivorship.
Phillip Yeoh, Wladyslawa Czuber‐Dochan, Simon Aylwin, Jackie Sturt   +3 more
wiley   +1 more source

Cushing's syndrome caused by intra‐adrenocortical adrenocorticotropic hormone in a dog

Journal of Veterinary Internal Medicine, Volume 36, Issue 1, Page 264-271, January/February 2022., 2022
Abstract A 13‐year‐old Labrador retriever was diagnosed with Cushing's syndrome (CS) caused by primary bilateral nodular adrenocortical hyperplasia with adrenocorticotropic hormone (ACTH) expression. The pituitary origin of CS was ruled out by suppression of plasma ACTH concentration and absence of a proliferative lesion on histological evaluation of ...
Elber A. Soler Arias, Víctor A. Castillo, Estelle Louiset, Herve Lefebvre   +3 more
wiley   +1 more source

Adrenal Myelolipoma Masquerading as an Adrenal Malignancy

Case Reports in Endocrinology, Volume 2022, Issue 1, 2022., 2022
An adrenal myelolipoma presenting with suspicious features may pose a diagnostic challenge to surgeons and endocrinologists. In this case report of an adult patient with undiagnosed congenital adrenal hyperplasia presenting with bilateral adrenal masses, we review his radiographic and clinical findings which were highly suspicious for adrenal ...
Davida A. Robinson, Margaret Kemeny, Juliana E. Muchinyi, Madiha Yasin, Nilda I. Montes, Sandeep Tuli, Radhika Jaiswal, Amanda Carter, Michal-Ann Derezil, Hanna Jang, David Reich, Wayne V. Moore   +11 more
wiley   +1 more source

Clinical Associations of Thyroid Hormone Levels with the Risk of Atherosclerosis in Euthyroid Type 2 Diabetic Patients in Central China

International Journal of Endocrinology, Volume 2020, Issue 1, 2020., 2020
Background. Thyroid function is associated with the etiology and pathogenesis of type 2 diabetes (T2D) and potentially contributes to the development of the complications of T2D. The association of thyroid hormones with atherosclerosis in euthyroid T2D patients is not clear. Purpose.
Limin Wang, Tingting Chen, Jiawei Yu, Huijuan Yuan, Xinru Deng, Zhigang Zhao, Claudio Casella   +6 more
wiley   +1 more source

Microgravity versus Microgravity and Irradiation: Investigating the Change of Neuroendocrine‐Immune System and the Antagonistic Effect of Traditional Chinese Medicine Formula

BioMed Research International, Volume 2020, Issue 1, 2020., 2020
During spaceflight, the homeostasis of the living body is threatened with cosmic environment including microgravity and irradiation. Traditional Chinese medicine could ameliorate the internal imbalance during spaceflight, but its mechanism is still unclear.
Haoru Zhu, Lin Zhang, Meng Qian, Tuo Shi, Fangxin Fan, Wenfei Li, Sitai Zhu, Ming Xie, Zhongquan Dai   +8 more
wiley   +1 more source

Effect of Hirsutella sinensis Fungus on the Hypothalamic‐Pituitary‐Adrenal Axis in Lewis Rats with Kidney‐Yang Deficiency Syndrome

Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Kidney‐yang deficiency syndrome (KYDS) is a classic syndrome in traditional Chinese medicine, which is mainly caused by damage to the hypothalamic‐pituitary‐adrenal (HPA) axis. Hirsutella sinensis fungus (HSF), an artificial substitute of Cordyceps sinensis, has been widely used in TCM.
Lizong Zhang, Jiali Lang, Lu Jin, Lushuai Jin, Beibei Cao, Xia Shao, Mingsun Fang, Yueqin Cai, Xia Liu, Huiying Fu, Qiyang Shou, Junqing Yang   +11 more
wiley   +1 more source

Multidisciplinary approach for patients with functional and non‐functional adrenal masses and review of the literature

Health Science Reports, Volume 1, Issue 3, March 2018., 2018
Abstract Background Adrenal incidentalomas are adrenal masses that are discovered by imaging tests performed for other reasons. Aims In this retrospective study, we analysed 229 Turkish patients with adrenal masses and who presented with or without complaints.
Gamze Akkuş, Mehtap Evran, Murat Sert, Fesih Ok, Tamer Tetiker   +4 more
wiley   +1 more source

Functional plurihormonal adrenal oncocytoma: case report and literature review

Clinical Case Reports, Volume 6, Issue 1, Page 37-44, January 2018., 2018
We present a 27‐year‐old woman with an adrenal oncocytoma. This is a very rare entity. We provide a review of the clinical, biochemical and pathological features of cases reported in the literature. Key Clinical Message We present a 27‐year‐old woman with an adrenal oncocytoma. This is a very rare entity.
Pablo René Costanzo, Andrea Laura Paissan, Pablo Knoblovits   +2 more
wiley   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source