Successful laparotomic ethanol ablation for an adrenal tumour in a dog [PDF]
Adrenalectomy is the gold standard for canine adrenal tumours, but not always recommended due to patient age, underlying conditions and perioperative mortality. Ethanol ablation is an alternative in human medicine for poor surgical candidates.
Shimon Furusato +3 more
doaj +3 more sources
Molecular and Genetics Perspectives on Primary Adrenocortical Hyperfunction Disorders [PDF]
Adrenocortical disorders encompass a broad spectrum of conditions ranging from benign hyperplasia to malignant tumors, significantly disrupting hormone balance and causing a variety of clinical manifestations. By leveraging next-generation sequencing and in silico analyses, recent studies have uncovered the genetic and molecular pathways implicated in ...
Sanggu Kim, Soochong Kim, Kim Sanggu
exaly +4 more sources
Immunohistochemical expression of CYP11A1, CYP11B, CYP17, and HSD3B2 in functional and nonfunctional canine adrenocortical tumors. [PDF]
Abstract Background Functionality of human adrenal tumors is inferred by CYP11B1 (cortisol synthase) expression, CYP11B2 (aldosterone synthase) expression, or both. Hypothesis/Objectives Nonfunctional canine adrenal tumors have low expression of steroidogenic enzymes, whereas aldosterone‐producing tumors express CYP11B, and cortisol‐producing tumors ...
Allan F, Watson AH, Syme HM.
europepmc +2 more sources
Ectopic corticotroph syndrome [PDF]
INTRODUCTION Endogenous Cushing's syndrome is a clinical state resulting from prolonged, inappropriate exposure to excessive endogenous secretion of Cortisol and hence excess circulating free cortisol, characterized by loss of the normal feedback ...
Penezić Zorana +5 more
doaj +1 more source
Lived experience of people with adrenocortical carcinoma and associated adrenal insufficiency
ACC appears to have high impact on lived experience of patients including their wellbeing and AI management. Further qualitative study is needed to understand the interactions of these two conditions, it's influences on patients' journey and survivorship.
Phillip Yeoh +3 more
wiley +1 more source
Cushing's syndrome caused by intra‐adrenocortical adrenocorticotropic hormone in a dog
Abstract A 13‐year‐old Labrador retriever was diagnosed with Cushing's syndrome (CS) caused by primary bilateral nodular adrenocortical hyperplasia with adrenocorticotropic hormone (ACTH) expression. The pituitary origin of CS was ruled out by suppression of plasma ACTH concentration and absence of a proliferative lesion on histological evaluation of ...
Elber A. Soler Arias +3 more
wiley +1 more source
Adrenal Myelolipoma Masquerading as an Adrenal Malignancy
An adrenal myelolipoma presenting with suspicious features may pose a diagnostic challenge to surgeons and endocrinologists. In this case report of an adult patient with undiagnosed congenital adrenal hyperplasia presenting with bilateral adrenal masses, we review his radiographic and clinical findings which were highly suspicious for adrenal ...
Davida A. Robinson +11 more
wiley +1 more source
Modern views on Cushing’s disease treatment
The aim. To choose the most optimal method of Cushing's disease (CD) therapy based on the clinical picture and the previous treatment efficacy. CD is a serious endocrine system disease caused by corticotropinoma or ectopic ACTH-producing adenoma ...
V. G. Kadzharian, O. O. Soloviuk
doaj +1 more source
Evaluation of adrenal tumors and analysis of the metabolic profile of patients with incidentaloma [PDF]
Introduction: Advances in imaging methods have led to an increasingly frequent diagnosis of adrenal gland lesions as incidental findings. Despite progress in this field, there is still limited information regarding the epidemiology of the clinical and ...
PEDRO VICTOR GONÇALVES MONTALVÃO +5 more
doaj +1 more source
Patient-specific workup of adrenal incidentalomas
Purpose: : To develop a clinical prediction model to predict a clinically relevant adrenal disorder for patients with adrenal incidentaloma. Materials and methods: : This retrospective study is approved by the institutional review board, with waiver of ...
Romy R. de Haan +6 more
doaj +1 more source

