Results 71 to 80 of about 1,062,529 (285)

Burden of Oral Corticosteroid Use in Severe Asthma: Challenges and Opportunities

Allergy, EarlyView.
ABSTRACT Over the past 70 years, oral corticosteroids (OCS) have played an important role in the management of acute and chronic asthma; however, their use is associated with an increased incidence of adverse events, chronic diseases such as osteoporosis and diabetes, and mortality, as well as increased healthcare resource utilization and costs ...
G. Walter Canonica, Celeste Porsbjerg, David B. Price, Michael E. Wechsler, Liam G. Heaney, Nicola A. Hanania, Rebecca Gall, Nami Pandit‐Abid, Juby A. Jacob‐Nara, Harry J. Sacks   +9 more
wiley   +1 more source

Internal jugular vein: Peripheral vein adrenocorticotropic hormone ratio in patients with adrenocorticotropic hormone-dependent Cushing′s syndrome: Ratio calculated from one adrenocorticotropic hormone sample each from right and left internal jugular vein during corticotrophin releasing hormone stimulation test

Indian Journal of Endocrinology and Metabolism, 2013
Background: Demonstration of central: Peripheral adrenocorticotropic hormone (ACTH) gradient is important for diagnosis of Cushing′s disease. Aim: The aim was to assess the utility of internal jugular vein (IJV): Peripheral vein ACTH ratio for diagnosis ...
Sachin Chittawar, Saptarshi Bhattacharya, Jai Prakash Sahoo, Siva Prakash, Ashu Seith Bhalla, Devasenathipathy Kandasamy, Arundeep Arora, Nandita Gupta, Nikhil Tandon, Ravinder Goswami, Rajesh Khadgawat, Viveka P Jyotsna, Ashish Kumar Karak, Chandra Sekhar Bal, Ravindra Mohan Pandey, Guresh Kumar, Ariachery C Ammini   +16 more
doaj   +1 more source

Treatment of idiopathic FSGS with adrenocorticotropic hormone gel.

American Society of Nephrology. Clinical Journal, 2013
BACKGROUND AND OBJECTIVES Adrenocorticotropic hormone (ACTH) has shown efficacy as primary and secondary therapy for nephrotic syndrome due to membranous nephropathy. The data on using ACTH to treat idiopathic FSGS are limited.
Jonathan J. Hogan, A. Bomback, Kshama Mehta, P. Canetta, Maya K. Rao, G. Appel, J. Radhakrishnan, R. Lafayette   +7 more
semanticscholar   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanisms

Kidney International, 2013
Adrenocorticotropic hormone (ACTH) has a renoprotective effect in chronic kidney disease; however, its effect on acute kidney injury (AKI) remains unknown. In a rat model of tumor necrosis factor (TNF)–induced AKI, we found that ACTH gel prevented kidney
Jin Si, Y. Ge, S. Zhuang, Li Juan Wang, Shan Chen, R. Gong   +5 more
semanticscholar   +1 more source

Endocrine Abnormalities and Growth Pattern in Single Large‐Scale Mitochondrial DNA Deletion Syndromes

Acta Paediatrica, EarlyView.
ABSTRACT Aim To assess the prevalence of endocrine disorders and investigate growth patterns in single large‐scale mitochondrial DNA deletion syndromes (SLSMDs). Methods A retrospective study of all children with SLSMD who attended Sheba Medical Center, Israel, from February 2017 to September 2024.
Ayman Daka, Einat Lahav, Omer Bar Yosef, Yoav Bolkier, Yael Levy‐Shraga, Yair Anikster, Elad Jacoby, Noah Gruber   +7 more
wiley   +1 more source

Multiple Sclerosis, Relapses, and the Mechanism of Action of Adrenocorticotropic Hormone

Frontiers in Neurology, 2013
Relapses in multiple sclerosis (MS) are disruptive and frequently disabling for patients, and their treatment is often a challenge to clinicians. Despite progress in the understanding of the pathophysiology of MS and development of new treatments for ...
A. P. Ross, A. Ben-Zacharia, C. Harris, Jennifer Smrtka   +3 more
semanticscholar   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Bilateral primary adrenal lymphoma

Journal of General and Family Medicine, EarlyView.
Rio Shimizu, Shogo Shirota
wiley   +1 more source

Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?

British Journal of Pharmacology, EarlyView.
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio, Luiz G. S. Branco, Fernanda Brognara, Patrícia Passaglia, Roberta Foresti, Roberto Motterlini   +5 more
wiley   +1 more source