Results 111 to 120 of about 18,670 (220)

Adrenomedullin and Adrenomedullin-Targeted Therapy As Treatment Strategies Relevant for Sepsis

Frontiers in Immunology, 2018
Sepsis remains a major medical challenge, for which, apart from improvements in supportive care, treatment has not relevantly changed over the last few decades.
Christopher Geven, Christopher Geven, Matthijs Kox, Matthijs Kox, Peter Pickkers, Peter Pickkers   +5 more
doaj   +1 more source

Association of a genetic variant in adrenomedullin gene with its plasma level [PDF]

, 2011
published_or_final_versionThe 16th Annual Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong, 22 January 2011. In Hong Kong Medical Journal, 2011, v. 17, suppl. 1, p.
Cherny, SS, Cheung, BMY, Lam, KSL, Lam, TH, Leung, RYH, Ong, KL, Sham, PC, Tso, AWK   +7 more
core  

Cardiovascular Involvement in Sepsis. [PDF]

, 2016
This special issue wants to contribute to a better understanding of cardiac involvement in sepsis. Sepsis is a complex syndrome that has recently been defined as “life-threatening organ dysfunction due to a dysregulated host response to infection”.
Fineschi, V., Palmiere, C., Sergi, C., Turillazzi, E.   +3 more
core   +5 more sources

Identification of hypoxic macrophages in glioblastoma: Unveiling therapeutic insights from tumour microenvironment analysis

Clinical and Translational Medicine
Tumor‐associatedmacrophages (TAMs) exhibit remarkable heterogeneity in glioblastoma. Spatially resolved single‐cell transcriptomic studies identified a monocyte‐derived TAM subset localized in the peri‐necrotic niche, driven by hypoxic cues to acquire ...
Zhen Qin, Xiu‐Wu Bian, Yu Shi
doaj   +1 more source

Bio-Adrenomedullin and Dipeptidyl Peptidase 3 as Novel Sepsis Biomarkers in the Emergency Department and the Intensive Care Unit: A Narrative Review

Medicina
Early recognition and timely treatment of sepsis and septic shock is vital. Despite appropriate management, mortality and morbidity rates remain high. In recent years, many of the research efforts have been directed towards finding novel biomarkers that ...
Ioannis Ventoulis, Christos Verras, Dionysis Matsiras, Vasiliki Bistola, Sofia Bezati, John Parissis, Effie Polyzogopoulou   +6 more
doaj   +1 more source

Caffeoylquinic acid enhances proliferation of oligodendrocyte precursor cells

Translational Neuroscience, 2017
This report evaluates the protective effect of caffeoylquinic acid (CA) injury to oligodendrocyte precursor cells (OPCs) by promoting the formation of oligodendrocytes.
Yanqin Ying, Shaohua Chen, Jing Tang, Nan Li   +3 more
doaj   +1 more source

Adrenomedullin orchestrates treatment resistance in hepatocellular carcinoma via immune microenvironment remodeling

Frontiers in Genetics
BackgroundHepatocellular carcinoma (HCC) displays marked cellular heterogeneity and immune microenvironment complexity that fundamentally influence transcatheter arterial chemoembolization (TACE) treatment responses and patient outcomes.
Xixi Gao, Yongliang Sun, Jia Huang, Li Xu, Hanchun Huang, Zhiying Yang   +5 more
doaj   +1 more source

The Cytokine response of rat macrophages to lipopolysaccharide is modulated by adrenomedullin [PDF]

, 2003
published_or_final_versio
Cheung, BMY, Li, CYY, Tang, F, Wong, LYF
core  

Plasma adrenomedullin levels, body fluid status, and end-stage renal failure [PDF]

, 1998
Hartmann, G., Lang, Susanne M., Schiffl, Helmut, Sitter, Thomas, Toepfer, Marcel   +4 more
core   +1 more source

Diabetes Mellitus and Reprogrammed Glucose Metabolism in Pancreatic Cancer: Features for Clinical Translation [PDF]

, 2016
The reprogrammed metabolism of cancer cells underlies the shift of glucose energetics from the highly efficient oxidative phosphorylation to the less efficient aerobic glycolysis, the Warburg effect.
BASSO, DANIELA, Fogar, Paola, PADOAN, ANDREA, PLEBANI, MARIO, ZAMBON, CARLO-FEDERICO   +4 more
core