Results 91 to 100 of about 11,146 (212)
Fetomaternal adrenomedullin levels in diabetic pregnancy.
, 2001 We investigated whether maternal and fetoplacental adrenomedullin, a newly discovered hypotensive peptide involved in the insulin regulatory system, is modified in diabetic pregnancy.
E. Marinoni +5 more
core +1 more source
Adrenomedullin in Heart Failure
Hypertension Research, 2003 Patients with heart failure have frequently been reported to show elevated levels of plasma adrenomedullin. These levels generally correlate with severity of hemodynamic dysfunction and also with neurohormonal indices which are activated according to the severity of heart failure.
NICHOLLS, M. Gary +6 more
openaire +3 more sources
Adrenomedullin and organ protection
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2004 アドレノメデュリンは我が国で発見された降圧ペプチドであるが, 最近では抗酸化作用を含めた pleiotropic effect が注目されている, 各種基礎検討特にノックアウトマウスの解析から, アドレノメデュリンの臓器保護作用や生殖系への作用を有することが明らかとなった. さらにホモロジー検索から新たなペプチドが発見されている. SNP解析も行われており, 疾患との関連性が明らかにされることが期待される. さらに, 最近では臨床応用として体液量の指標としての測定意義や, 動物実験で証明された臓器保護作用をヒトに応用する臨床検討が進行している. アドレノメデュリンは今後のさらなる発展が期待されるペプチドである.
Shimosawa, Tatsuo, Fujita, Toshiro
openaire +3 more sources
Adrenomedullin and Adrenomedullin-Targeted Therapy As Treatment Strategies Relevant for Sepsis
Frontiers in Immunology, 2018 Sepsis remains a major medical challenge, for which, apart from improvements in supportive care, treatment has not relevantly changed over the last few decades.
Christopher Geven +5 more
doaj +1 more source
Adrenomedullin, a new peptide, in patients with insulinoma
, 2001 It has been demonstrated that adrenomedullin, a newly discovered peptide, affects the release of insulin from pancreatic islets cells, suggesting a role in the insulin-regulating system.
E. Marinoni +7 more
core +1 more source
Clinical and Translational MedicineTumor‐associatedmacrophages (TAMs) exhibit remarkable heterogeneity in glioblastoma. Spatially resolved single‐cell transcriptomic studies identified a monocyte‐derived TAM subset localized in the peri‐necrotic niche, driven by hypoxic cues to acquire ...
Zhen Qin, Xiu‐Wu Bian, Yu Shi
doaj +1 more source
, 2016 In the last few years, adipose tissue (AT) has been widely investigated and has been revealed to act as a real endocrine organ, secreting various active biomolecules named adipokines, involved in the development of obesity-related diseases.
Iacobellis G., Malavazos A. E.
core
MedicinaEarly recognition and timely treatment of sepsis and septic shock is vital. Despite appropriate management, mortality and morbidity rates remain high. In recent years, many of the research efforts have been directed towards finding novel biomarkers that ...
Ioannis Ventoulis +6 more
doaj +1 more source
Plasma adrenomedullin levels, body fluid status, and end-stage renal failure [PDF]
, 1998 Lang, Susanne M. +4 more
core +1 more source
Thrombin rapidly digests adrenomedullin: Synthesis of adrenomedullin analogs resistant to thrombin
, 2020 Yayoi Nishimoto, Sayaka Nagata, Emiko Akashi, Motoo Yamasaki, Kazuo Kitamura, Thrombin rapidly digests adrenomedullin: Synthesis of adrenomedullin analogs resistant to thrombin, Biochemical and Biophysical Research Communications, Volume 529, Issue 3 ...
北村, 和雄 +18 more
core