Results 71 to 80 of about 11,146 (212)
Adrenomedullin inhibits adipogenesis under transcriptional control of insulin.
, 2007 International audienceWe generated preadipocyte cell lines impaired in adrenomedullin production through integration of an adrenomedullin small interfering RNA expression vector.
Smih, Fatima +4 more
core +1 more source
The Journal of Physiology, Volume 604, Issue 12, Page 5031-5060, 15 June 2026.Abstract figure legend Preglomerular pericyte‐like SMMHC+ vascular smooth muscle cells (VSMCs) display marked endocrine plasticity. Hypotension caused by salt depletion and angiotensin‐converting enzyme (ACE) inhibition induces a reversible transformation of these VSMCs toward an endocrine state that produces renin.
Bettina K. M. Firmke +4 more
wiley +1 more source
Adrenomedullin: Its role in the cardiovascular system
, 2004 Adrenomedullin is a 52-amino acid peptide that was first isolated from human pheochromocytoma. Subsequently, it was found to be distributed widely in the body, including throughout the cardiovascular system.
Li, CYY, Wong, LYF, Cheung, BMY
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The Role of Adrenomedullin in the Renal NADPH Oxidase and (Pro)renin in Diabetic Mice
Journal of Diabetes Research, 2013 Adrenomedullin has an antioxidative action and protects organs in various diseases. To clarify the role of adrenomedullin in diabetic nephropathy, we investigated the NADPH oxidase expression, renin-secreting granular cell (GC) hyperplasia, and ...
Michio Hayashi +3 more
doaj +1 more source
ACR Open Rheumatology, Volume 8, Issue 5, May 2026.Objective Proadrenomedullin (pro‐ADM) is a peptide implicated in immunomodulation, with higher levels observed in inflammatory conditions, cardiovascular impairment, and sepsis. Although extensively studied in acute disorders, its potential as a biomarker in inflammatory arthritis remains underexplored.
Nefeli Stavroula Papastathopoulou +10 more
wiley +1 more source
Amniotic fluid concentrations of adrenomedullin.
, 1999 To determine whether adrenomedullin levels in amniotic fluid were associated with preterm labor. We measured immunoreactive adrenomedullin in amniotic fluid collected by amniocentesis from 36 women with clinical diagnosis of preterm labor or preterm ...
MARINONI, EMANUELA +5 more
core +1 more source
How does type 2 diabetes modify the risk of Alzheimer's disease?
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract Type 2 diabetes (T2D) and Alzheimer's disease (AD) are both increasing exponentially worldwide. T2D has also been identified as one of 14 modifiable risk factors for dementia, but the mechanism is unknown. T2D could promote dementia via vascular or AD neuropathological changes, and mechanistic hypotheses include central insulin resistance and ...
G. T. Sutherland +7 more
wiley +1 more source
, 2016 A dendritikus sejtek (DC) az immunfolyamatok szabályozása során részt vesznek a naiv T-sejtek további differenciálódásának irányításában. Ezeket a TH1- és TH17-sejtek kialakulásának irányába terelhetik, mely által elősegítik a szervezetben zajló ...
Jakab, Ágnes
core
Targeting Tumor Stroma: Current Challenges and Future Directions
MedComm, Volume 7, Issue 5, May 2026.Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
wiley +1 more source