Results 61 to 70 of about 11,146 (212)
Differential roles of interleukin-6 and adrenomedullin in early diagnosis and mortality predictions in late-onset neonatal sepsis [PDF]
Clinical and Experimental PediatricsBackground Diagnosing and predicting neonatal sepsis is challenging because of its nonspecific symptoms, lack of diagnostic criteria consensus, and absence of early, sensitive, and specific diagnostic laboratory tests.
Emilly Henrique dos Santos +6 more
doaj +1 more source
International Endodontic Journal, Volume 59, Issue 7, Page 1402-1415, July 2026.ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl +10 more
wiley +1 more source
Role of Adrenomedullin in Lyme Disease
, 2010 Borrelia burgdorferi stimulates a strong inflammatory response during infection of a mammalian host. To understand the mechanisms of immune regulation employed by the host to control this inflammatory response, we focused our studies on ...
Shizuo Akira +6 more
core +1 more source
Calcium:Calcitonin gene-related peptide and adrenomedullin receptors
, 2021 Calcitonin gene-related peptide (CGRP), adrenomedullin (AM) and adrenomedullin 2 (AM2) are related peptides, which are potent vasodilators. The receptors for these peptides are unusual, comprising a G-protein-coupled receptor (GPCR) with receptor ...
Poyner, David +7 more
core +1 more source
Bioactive Adrenomedullin in Dogs with Sepsis and Septic Shock: A Prospective, Case-Control Study
AnimalsSepsis and septic shock are leading causes of morbidity and mortality in both humans and dogs, and early diagnosis is crucial for improving outcomes. This study aimed to evaluate bioactive adrenomedullin (bio-ADM) concentrations in dogs with septic shock
Eirini Chrysovergi +4 more
doaj +1 more source
Effect of liraglutide on atrial natriuretic peptide, adrenomedullin, and copeptin in PCOS
Endocrine Connections, 2018 Context: Women with polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease (CVD), and biomarkers can be used to detect early subclinical CVD.
Signe Frøssing +4 more
doaj +1 more source
Adrenomedullin and tumour angiogenesis [PDF]
British Journal of Cancer, 2005 The angiogenic activity of peptide adrenomedullin (AM) was first shown in 1998 . Since then, a number of reports have confirmed the ability of AM to induce the growth and migration of isolated vascular endothelial and smooth muscle cells in vitro and to promote angiogenesis in xenografted tumours in vivo. In addition, knockout murine models point to an
Nikitenko, L. L. +4 more
openaire +3 more sources
Treatment of bone disorders with adrenomedullin or adrenomedullin agonists
, 2002 A method for promoting bone growth in a patient (e.g., a mammal such as a human) said method including the step of administering a therapeutically effective amount of adrenomedullin or an adrenomedullin agonist to said ...
Reid, Ian Reginald +3 more
core +1 more source
Circulating microparticles, protein C, free protein S and endothelial vascular markers in children with sickle cell anaemia [PDF]
Journal of Extracellular Vesicles, 2015 Introduction: Circulating microparticles (MP) have been described in sickle cell anaemia (SCA); however, their interaction with endothelial markers remains unclear.
Andrea Piccin +11 more
doaj +1 more source
Med Research, Volume 2, Issue 2, Page 280-308, June 2026.White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source