Results 51 to 60 of about 11,146 (212)

Plasma adrenomedullin level is related to plasma interleukin-6 and a polymorphism in the adrenomedullin gene

, 2011
INTRODUCTION: Adrenomedullin is involved in inflammation and like interleukin-6 (IL-6) and C-reactive protein (CRP), is a good biomarker of cardiovascular risk.
Cherny, SS, Lam, TH, Tso, AWK, Lam, KSL, Cheung, BMY, Leung, RYH, Ong, KL, Sham, PC   +7 more
core   +1 more source

Adrenomedullin: A Novel Therapeutic for the Treatment of Inflammatory Bowel Disease

Biomedicines, 2021
Adrenomedullin (AM) is a bioactive peptide with various physiological functions, including vasodilation, angiogenesis, anti-inflammation, organ protection, and tissue repair.
Shinya Ashizuka, Toshihiro Kita, Haruhiko Inatsu, Kazuo Kitamura   +3 more
doaj   +1 more source

Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia

European Journal of Haematology, EarlyView.
ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco, Diane S. Krause, Sara T. Olalla Saad   +2 more
wiley   +1 more source

TRIM32 controls timely cell cycle exit in muscular differentiation through downregulation of c‐Myc mRNA

The FEBS Journal, EarlyView.
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong, Elisa Lazzari, Sabrina Pacor, Simeone Dal Monego, Erica Piovesan, Danilo Licastro, Germana Meroni   +6 more
wiley   +1 more source

Inflammation: Complexity and significance of cellular and molecular responses

Journal of Acute Disease
Inflammation is a multifaceted cellular and molecular response triggered by injury, infection, or various pathological conditions. Serving as a protective defense mechanism, the inflammatory response involves clinical signs like redness, swelling, pain ...
Serdar Özdemir
doaj   +1 more source

Plasma bio-adrenomedullin is a marker of acute heart failure severity in patients with acute coronary syndrome

International Journal of Cardiology: Heart & Vasculature, 2019
Background: The assessment of acute heart failure (AHF) in patients with acute coronary syndrome (ACS) is challenging. This study tested whether measuring plasma adrenomedullin in patients admitted for ACS provides valuable information regarding the ...
Mattia Arrigo, Jiri Parenica, Eva Ganovska, Marie Pavlusova, Alexandre Mebazaa   +4 more
doaj   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Adrenomedullin is not Related to Acute Hypoxic Pulmonary Vascular Response in Patients with Chronic Respiratory Disease [PDF]

, 1999
In the present study, acute hypoxia was induced in 19 patients with chronic respiratory disease to evaluate the corre lation between pulmonary circulation kinetics and adrenomedullin (AM) levels.
Miyahara, Yoshiyuki, Yakabe, Kazuaki, Kohno, Shigeru, Furukawa, Katsuyuki, Ikeda, Satoshi, Yamaguchi, Kenji, Matsushita, Tetsuro, Iwasaki, Tadasu   +7 more
core  

Influence of labor on fetoplacental adrenomedullin concentrations

, 2001
OBJECTIVE: Circulating adrenomedullin is increased in pregnancy, and placental and fetal membranes participate significantly in its secretion. Recent studies have suggested a potential role for this peptide in the regulation of fetoplacental circulation ...
Roberta Poverini, MARINONI, EMANUELA, COSMI, Ermelando, Barbara Villaccio, DI IORIO, Romolo, LETIZIA, Claudio, ALO', Piero Luigi   +6 more
core   +1 more source

The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies

Headache: The Journal of Head and Face Pain, Volume 66, Issue 7, Page 1628-1643, July/August 2026.
Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone, Marcello Silvestro, Antonio Munafò, Marina Romozzi, Pierangelo Geppetti, Antonio Russo   +5 more
wiley   +1 more source