Results 171 to 180 of about 11,146 (212)
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Regulatory Peptides, 2003
Adrenomedullin (AM) is a pluripotent hormone with structural similarities to calcitonin gene-related peptide (CGRP), which is expressed by many tissues in the body and shows a remarkable range of effects mediated by paracrine/autocrine and possibly endocrine mechanisms.
E, Zudaire, A, Martínez, F, Cuttitta
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Adrenomedullin (AM) is a pluripotent hormone with structural similarities to calcitonin gene-related peptide (CGRP), which is expressed by many tissues in the body and shows a remarkable range of effects mediated by paracrine/autocrine and possibly endocrine mechanisms.
E, Zudaire, A, Martínez, F, Cuttitta
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Regulatory Peptides, 2003
Adrenomedullin (AM) is a multifunctional regulatory peptide that is produced and secreted by various types of cells. We showed the presence of high concentrations of adrenomedullin-immunoreactivity in the vitreous fluid, and the levels were elevated in patients with proliferative vitreoretinopathy.
Reiko, Udono-Fujimori +5 more
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Adrenomedullin (AM) is a multifunctional regulatory peptide that is produced and secreted by various types of cells. We showed the presence of high concentrations of adrenomedullin-immunoreactivity in the vitreous fluid, and the levels were elevated in patients with proliferative vitreoretinopathy.
Reiko, Udono-Fujimori +5 more
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Microscopy Research and Technique, 2002
AbstractAdrenomedullin (AM) was originally characterized in extracts of an adrenal medullary tumor. Since this original finding the peptide and its mRNA have also been found in the adrenal cortex, specifically, in the cells of the aldosterone‐secreting zona glomerulosa.
Supriya, Kapas, Joy P, Hinson
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AbstractAdrenomedullin (AM) was originally characterized in extracts of an adrenal medullary tumor. Since this original finding the peptide and its mRNA have also been found in the adrenal cortex, specifically, in the cells of the aldosterone‐secreting zona glomerulosa.
Supriya, Kapas, Joy P, Hinson
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Adrenomedullin in hypertension
Current Hypertension Reports, 2000Introduction Adrenomedullin, a 52-amino acid peptide, was discovered in 1993 in human pheochromocytoma tissue. The initial report documented not only its structure, but also the fact that when the hormone was administered to experimental animals, it had a potent and long-lasting hypotensive effect.
R D, Troughton +4 more
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Arteriosclerosis, Thrombosis, and Vascular Biology, 2005 Adrenomedullin (AM) is a vasodilator peptide having a wide range of biological actions such as reduction of oxidative stress and inhibition of endothelial cell apoptosis. The AM gene is expressed in vascular walls, and AM was found to be secreted from cultured vascular endothelial cells, smooth muscle cells, and adventitial fibroblasts.
Johji Kato +2 more
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Adrenomedullin is a novel adipokine: Adrenomedullin in adipocytes and adipose tissues
Peptides, 2007Adrenomedullin (AM) is a multifunctional regulatory peptide that is produced and secreted by various types of cells. The production and the secretion of AM have been demonstrated in cultured adipocytes and adipose tissues. Inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharide are strong stimulators for AM ...
Yin, Li +5 more
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Adrenomedullin in vascular diseases
Current Hypertension Reports, 2004A novel vasodilator, adrenomedullin (AM), which acts as an autocrine/paracrine factor in cardiovascular system, has antiproliferative and antimigrative effects. AM gene transfer prevents the development of cuff-induced vascular injury. Moreover, AM knockout mice exhibited an increase in angiotensin (Ang) II/salt loading-induced coronary arterial lesion,
Katsuyuki, Ando +2 more
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Adrenomedullin in perinatal medicine
Regulatory Peptides, 2003This review will consider whether adrenomedullin (AM) plays a role in the different aspects of perinatal medicine: contributing to maternal systemic vasodilatation during pregnancy, regulating uterine and placental blood flow, being involved in the process of implantation and participating in uterine quiescence prior to parturition.
DI IORIO, Romolo +3 more
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