Results 31 to 40 of about 2,492,374 (226)

Association of asthma with coronary heart disease: A meta analysis of 11 trials.

PLoS ONE, 2017
PurposeWhile the relationship of asthma and coronary heart disease (CHD) (a specific manifestation of cardiovascular disease) has not been described consistently, we tried to defined this relation and explore the influence of gender and asthma status ...
Lida Wang, Shuyan Gao, Mingdong Yu, Zhixin Sheng, Wei Tan   +4 more
doaj   +1 more source

Asthma in Children and Adults—What Are the Differences and What Can They Tell us About Asthma?

Frontiers in Pediatrics, 2019
Asthma varies considerably across the life course. Childhood asthma is known for its overall high prevalence with a male predominance prior to puberty, common remission, and rare mortality.
Michelle Trivedi, Michelle Trivedi, Eve Denton, Eve Denton   +3 more
doaj   +1 more source

Association Between Environmental Factors and Asthma Using Mendelian Randomization: Increased Effect of Body Mass Index on Adult-Onset Moderate-to-Severe Asthma Subtypes

Frontiers in Genetics, 2021
Although asthma is one of the most common chronic diseases throughout all age groups, its etiology remains unknown, primarily due to its heterogeneous characteristics.
Tae-Woong Ha, Hae-Un Jung, Dong Jun Kim, Eun Ju Baek, Won Jun Lee, Ji Eun Lim, Han Kyul Kim, Ji-One Kang, Bermseok Oh   +8 more
doaj   +1 more source

Respiratory health in cleaners in Northern Europe : is susceptibility established in early life? [PDF]

, 2015
There is some evidence that maternal smoking increases susceptibility to personal smoking's detrimental effects. One might question whether early life disadvantage might influence susceptibility to occupational exposure.; In this cross-sectional study we
Svanes, C., Dratva, J., Schlünssen, V., Dan Norbäck (2143342), Skorge, Trude Duelien, Tor Aasen, Dan Norbäck, Real, Francisco Gómez, Bratveit, M., Wieslander, G., Randi Jacobsen Bertelsen, Julia Dratva, Rain Jögi (769222), Macsali, Ferenc, Norbäck, D., Forsberg, Bertil, Wieslander, Gunilla, Gomez Real, F., Torben Sigsgaard (60516), Omenaas, Ernst Reidar, Omenaas, E.R., Ferenc Macsali, Ernst Reidar Omenaas (769224), Holm, Mathias,, Forsberg, B., Schlünssen, Vivi, Jan-Paul Zock (489691), Bertelsen, R. J., Mathias Holm (769221), Bertil Forsberg, Svanes, O, Christer Janson, Thorarin Gislason, Mathias Holm, Cecilie Svanes (59836), Norbäck, Dan, Holm, M., Øistein Svanes, Jan-Paul Zock, Omenaas, E. R., Zock, J. P., Julia Dratva (748527), Aasen, Tor, Sigsgaard, T., Aasen, T., Jögi, Rain, Joegi, Rain,, Svanes, Oistein, Gunilla Wieslander, Gislason, T., Christer Janson (83414), Tor Aasen (5664346), Macsali, F., Real, F. G., Ane Johannessen, Omenaas, Ernst, Gislason, Thorarin, Randi Jacobsen Bertelsen (769219), Svanes, O., Francisco Gómez Real (769225), Aasen, Tor Olav Brøvig, Øistein Svanes (769216), Bertelsen, Randi Jacobsen, Gomez Real, Francisco, Janson, Christer,, Janson, C., Trude Duelien Skorge (769217), Cecilie Svanes, Jögi, R., Thorarin Gislason (769220), Holm, Mathias, Vivi Schlünssen, Skorge, T. D., Ernst Reidar Omenaas, Francisco Gómez Real, Vivi Schlünssen (769226), Bråtveit, Magne, Zock, Jan-Paul, Norbäck, Dan,, Forsberg, Bertil,, Ferenc Macsali (769223), Bertil Forsberg (62630), Janson, Christer, Joegi, Rain, Torben Sigsgaard, Dratva, Julia, Johannessen, A., Trude Duelien Skorge, Ane Johannessen (769218), Duelien Skorge, T., Bertelsen, R.J., Sigsgaard, Torben, Gunilla Wieslander (60949), Rain Jögi, Zock, J.P., Svanes, Øistein, Svanes, Cecilie, Magne Bråtveit, Magne Bråtveit (691377), Wieslander, Gunilla,, Johannessen, Ane   +100 more
core   +2 more sources

Childhood Onset Adult Asthma: A Comparison of Asthma Development with Exposure to High and Reduced Levels of Air Pollution

Allergology International, 2005
Background: In the 1960s when air pollution levels were high in Kanagawa prefecture as same as in other Japanese metropolises, the prevalence of asthma increased distinctly.
Yuji Maeda, Takao Shida, Kazuo Akiyama
doaj   +1 more source

A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts

BMC Medical Genetics, 2019
Background The chitinase-like protein YKL-40 plays a major role in inhibiting the inflammasome. Deregulation of inflammasome activation is emerging as a key modulator of pathologic airway inflammation in patients with asthma.
Jun Kanazawa, Haruna Kitazawa, Hironori Masuko, Yohei Yatagai, Tohru Sakamoto, Yoshiko Kaneko, Hiroaki Iijima, Takashi Naito, Takefumi Saito, Emiko Noguchi, Satoshi Konno, Masaharu Nishimura, Tomomitsu Hirota, Mayumi Tamari, Nobuyuki Hizawa   +14 more
doaj   +1 more source

Age-related differences in associations between uncontrolled asthma, comorbidities and biomarkers in adult-onset asthma

, 2023
Objective: Adult-onset asthma is a recognized but heterogeneous phenotype and has been described to associate with poor asthma control. Knowledge about associations between clinical characteristics including comorbidities and control of adult-onset ...
Stridsman, Caroline, Linnea Hedman, Caroline Stridsman, Katja Warm, Rönmark, Eva, Anne Lindberg, Hedman, Linnea, Helena Backman, Backman, Helena, Eva Rönmark, Warm, Katja, Lindberg, Anne   +11 more
core   +1 more source

Asthma Phenotypes in Japanese Adults - Their Associations with the CCL5 ADRB2 Genotypes

Allergology International, 2013
Background: Cluster analyses were previously performed to identify asthma phenotypes underlying asthma syndrome. Although a large number of patients with asthma develop the disease later in life, these previous cluster analyses focused mainly patients ...
Yoshiko Kaneko, Hironori Masuko, Tohru Sakamoto, Hiroaki Iijima, Takashi Naito, Yohei Yatagai, Hideyasu Yamada, Satoshi Konno, Masaharu Nishimura, Emiko Noguchi, Nobuyuki Hizawa   +10 more
doaj   +1 more source

Increased levels of serum IL-17 and induced sputum neutrophil percentage are associated with severe early-onset asthma in adults

Allergy, Asthma & Clinical Immunology, 2021
Background Differences between adult patients with severe early-onset and late-onset asthma have not been well studied. Objectives To determine the phenotypic distinction regarding age at onset in patients with severe asthma.
Dandan Chen, Yu Zhang, Can Yao, Binbin Li, Sinian Li, Wenwen Liu, Rongchang Chen, Fei Shi   +7 more
doaj   +1 more source

Adult‐Onset Compared to Childhood‐Onset Asthma: Multifaceted Symptoms, Comorbidity, and Healthcare Burden

Clinical and Translational Allergy
In this study, we compared symptoms, comorbidities, and healthcare burden between childhood‐onset asthma (
Reshed Abohalaka, Selin Ercan, Lauri Lehtimäki, Daniil Lisik, Saliha Selin Ozuygur Ermis, Helena Backman, Madeleine Rådinger, Bright I. Nwaru, Hannu Kankaanranta   +8 more
doaj   +1 more source