Results 1 to 10 of about 79,467 (119)

CD11b Expression Level Measurement to Distinguish Asthma Phenotype in Pediatric Patients [PDF]

Avicenna Journal of Medicine
Background Inflammation is involved in asthma pathogenesis. Based on the majority of inflammatory cells found in blood samples, asthma is divided into neutrophilic and eosinophilic phenotype.
Tien Budi Febriani, Soeroyo Mahfudz, Emi Azmi Choironi, Ninda Devita, Adika Zhulhi Arjana, Muhammad Nur Imansyah   +5 more
doaj   +2 more sources

Association between chemokine receptor 3T51C gene polymorphism and different clinical asthma phenotypes in Egyptian asthmatic children

Egyptian Journal of Chest Disease and Tuberculosis, 2023
Background Asthma is a heterogeneous disorder, which is affected by interaction between genes and the surrounding environment. Chemokine receptor 3 (CCR3) which is expressed over eosinophils and Th2 lymphocytes has a significant role in chemoattraction ...
Magdy M. I. Zedan, Mona El wassefy, Islam Nour, Eman O Khashaba, Amal Osman, Eman El Sherbiny   +5 more
doaj   +1 more source

Prevalence of eosinophilic, atopic, and overlap phenotypes among patients with severe asthma in Saudi Arabia: a cross-sectional study

BMC Pulmonary Medicine, 2022
Background Eosinophilia is a significant factor in asthma severity; however, the prevalence of severe eosinophilic asthma in Saudi Arabia is largely unknown.
Hamdan Al-Jahdali, Siraj Wali, Amr S. Albanna, Riyad Allehebi, Hussein Al-Matar, Mohamed Fattouh, Maarten Beekman   +6 more
doaj   +1 more source

Proximity to Heavy Traffic Roads and Patient Characteristics of Late of Onset Asthma in an Urban Asthma Center

Frontiers in Medicine, 2021
Background: Traffic-related pollution is associated with the onset of asthma and the development of different phenotypes of asthma. Few studies have investigated the association between traffic proximity and late-onset of asthma (LOA) and early-onset ...
Ting-Yu Lin, Ting-Yu Lin, Horng-Chyuan Lin, Horng-Chyuan Lin, Yun-Sheng Liu, Yu-Lun Lo, Yu-Lun Lo, Chun-Hua Wang, Chun-Hua Wang, Po-Jui Chang, Po-Jui Chang, Chun-Yu Lo, Chun-Yu Lo, Shu-Min Lin, Shu-Min Lin   +14 more
doaj   +1 more source

Sex-Specific Genetic Determinants of Asthma-COPD Phenotype and COPD in Middle-Aged and Older Canadian Adults: An Analysis of CLSA Data

COPD, 2023
The etiology of sex differences in the risk of asthma-COPD phenotype and COPD is still not completely understood. Genetic and environmental risk factors are commonly believed to play an important role.
Ugochukwu Odimba, Ambikaipakan Senthilselvan, Jamie Farrell, Zhiwei Gao   +3 more
doaj   +1 more source

A NARRATIVE REVIEW ON BIOLOGICS IN THE MANAGEMENT OF ASTHMA: ASSESSING THE CURRENT LANDSCAPE.

Student's Journal of Health Research Africa, 2023
Monoclonal antibodies (mAbs) play a crucial role in the treatment of severe asthma. Physicians rely on patient-specific characteristics to determine the appropriate asthma classification for treatment.
Santanu Kumar Ghosh
doaj   +1 more source

TFR1 expression in induced sputum is associated with asthma severity [PDF]

PeerJ, 2022
Background Asthma is characterized as a chronic inflammatory airway disease. Iron accumulation is related to asthma pathogenesis. Transferrin receptor 1(TFR1) expression is associated with intracellular iron overload in macrophages.
Yang Wang, li Feng Gu, Xincheng Zhao, Chengping Hu, Qiong Chen   +4 more
doaj   +2 more sources

Evaluation of serum levels of interleukin-10 and transforming growth factor-β1 among Egyptian children with wheezy asthma phenotype

Egyptian Journal of Chest Disease and Tuberculosis, 2021
Background Asthma is known to be a heterogeneous disease that forms a problem in asthma management. Symptom-based asthma phenotyping with endotyping of the proposed phenotype is a trial to solve this problem.
Magdy M.E Zedan, Mohamed M Zedan, Afaf M El-Said, Ahmed M.H Badran, Yahya Wahba   +4 more
doaj   +1 more source

Airway inflammatory biomarkers in different asthma phenotypes

The Egyptian Journal of Bronchology, 2020
Background Asthma is a diverse disease with various phenotypes. Correlation of clinical asthma phenotypes with their underlying inflammatory biomarkers could help tailor asthma management and in turn improve the patient’s outcome.
Amal M. Osman, Afaf M. Elsaid
doaj   +1 more source

PRevalence of the Eosinophilic Phenotype Among SeveRE asthma patients in Lebanon: results of the PREPARE study

Allergy, Asthma & Clinical Immunology, 2023
Background The prevalence of eosinophilic asthma in Lebanon, one of the most severe phenotypes among severe asthma, is not known. This study aimed at determining the prevalence of the eosinophilic phenotype defined as an eosinophil count ≥ 300 cells/mm3 ...
Wajdi Abi Saleh, Zuhair Alameh, Zeina Aoun Bacha, Joudy Bahous, Pierre Bou Khalil, Zahia Chahine, Hassan Chami, Georges Dabar, Hassan Dheiny, Alfred Dib, Dany farhat, Carla Irani, Georges Juvelekian, Nadim Kanj, Bassam Mansour, Moussa Riachi, Mirna Waked, Mohamad Yassine, Carole Youakim, Salah Zeinedine, Fares Zaitoun   +20 more
doaj   +1 more source