Results 31 to 40 of about 789,460 (209)

Asthma Phenotypes

Seminars in Respiratory and Critical Care Medicine, 2012
The identification of phenotypes of asthma has a long history, but previous classifications have not identified clinically important differences in pathology, natural history, or treatment response. Progress has accelerated recently, fueled by the development of new techniques to assess airway disease, particularly noninvasive techniques to assess ...
openaire   +3 more sources

Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration [PDF]

ERJ Open Research, 2018
The World Asthma Phenotypes (WASP) study started in 2016 and has been conducted in five centres, in the UK, New Zealand, Brazil, Ecuador and Uganda.The objectives of this study are to combine detailed biomarker and clinical information in order to 1) better understand and characterise asthma phenotypes in high-income countries (HICs) and low and middle-
Pembrey, Lucy, Barreto, Mauricio, Douwes, Jeroen, Cooper, Philip, Henderson, John, Mpairwe, Harriet, Ardura-Garcia, Cristina, Chico, Martha, Brooks, Colin, Cruz, Alvaro, Elliott, Alison M., Figueiredo, Camila A., Langan, Sinéad M., Nassanga, Beatrice, Rodrigues, Laura C., Ring, Susan, Pearce, Neil   +16 more
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Phenotype-Guided Asthma Therapy: An Alternative Approach to Guidelines

Journal of Asthma and Allergy, 2021
Luis Pérez de Llano, David Dacal Rivas, Nagore Blanco Cid, Irene Martin Robles Head of the Pneumology Service, Lucus Augusti University Hospital, EOXI Lugo, Monforte, Cervo.
Pérez de Llano L, Dacal Rivas D, Blanco Cid N, Martin Robles I   +3 more
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Activation of aryl hydrocarbon receptor (AhR) in mesenchymal stem cells modulates macrophage polarization in asthma

Journal of Immunotoxicology, 2020
Macrophage polarization has been demonstrated to exert a vital role on asthma pathogenesis. Mesenchymal stem cells (MSC) have the capacity to modulate macrophage differentiation from a pro-inflammatory M1 phenotype toward an anti-inflammatory M2 ...
Zhuang Cui, Yuan Feng, Danqing Li, Taoping Li, Peisong Gao, Ting Xu   +5 more
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Biomarkers of inflammatory asthma phenotypes [PDF]

Medicinski Podmladak
Asthma is characterized by heterogeneity and variability in pathophysiologic mechanisms , clinical presentation, therapy response, and exacerbations. It is defined as a syndrome that is compromised by different endotypes and phenotypes.
Plavšić Aleksandra, Tomić-Spirić Vesna   +1 more
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Untangling asthma phenotypes and endotypes [PDF]

Allergy, 2012
AbstractAsthma phenotypes have been developed to address the complexities of the disease. However, owing to a lack of longitudinal studies, little is known about the onset as well as the stability of phenotypes. Distinguishing phenotypes with regard to the severity or duration of the disease is essential.
Agache I, Akdis C, Jutel M, Virchow JC
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Severe asthma in Japan

Allergology International, 2019
The characteristic phenotype of severe asthma in Japan seems to be distilled into the following two features: low incidence of obesity and high prevalence of patients with type 2 inflammation.
Hiroyuki Nagase
doaj   +1 more source

Predictive Value of Radiologic Central Compartment Atopic Disease for Identifying Allergy and Asthma in Pediatric Patients

Ear, Nose & Throat Journal, 2022
Introduction: Central compartment atopic disease (CCAD) has recently been suggested as a phenotype of chronic rhinosinusitis (CRS). This study aims to investigate the prevalence of the radiologic CCAD phenotype in CRS within a pediatric population and ...
Kijeong Lee MD, Tae Hoon Kim MD, PhD, Sang Hag Lee MD, PhD, Chang Ho Kang MD, PhD, Bo-Kyung Je MD, PhD, Saelin Oh MD, PhD   +5 more
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The global Asthma report 2014 [PDF]

, 2014
Provides up-to-date information about asthma, and summarises what is known and where the gaps lie. The report also makes recommendations to authorities on required actions.

core  

The Bronchial Microbiome and Asthma Phenotypes [PDF]

American Journal of Respiratory and Critical Care Medicine, 2013
Emerging data on the astounding breadth, depth, and functional capacity of the human microbiome are transforming our understanding of the determinants of health and disease (1). Studies of the gastrointestinal microbiome are already moving beyond broad associations, as of microbial diversity with the development of immune function in infants (2) and of
Yvonne J, Huang, Homer A, Boushey
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