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Asthma phenotypes in childhood [PDF]
Current Opinion in Allergy & Clinical Immunology, 2016 This review describes the literature over the past 18 months that evaluated childhood asthma phenotypes, highlighting the key aspects of these studies, and comparing these studies to previous ones in this area.Recent studies on asthma phenotypes have identified new phenotypes on the basis of statistical analyses (using cluster analysis and latent class
Monica B, Reddy, Ronina A, Covar
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The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype [PDF]
, 2013 We previously demonstrated inhibition of ovalbumin (OVA)-induced allergic airway hyper-responsiveness in the mouse using ES-62, a phosphorylcholine-containing glycoprotein secreted by the filarial nematode, Acanthocheilonema viteae.
Al-Riyami, Lamyaa +8 more
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, 2021 Asthma is a common complex and heterogeneous respiratory disease with an increasing prevalence in developed countries. Asthma is a disease consisting of different phenotypes that are driven by different mechanistic pathways (endotypes).
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Current Allergy and Asthma Reports, 2009 The many roads leading to the syndrome of asthma have proven to be intricately interconnected. The chronic inflammation of asthma is characterized by airway hyperreactivity and variable reversibility. Past classification systems relied on assessment of daily impairment and the distinction between intrinsic (nonallergic) and extrinsic (allergic).
Handoyo, Steve, Rosenwasser, Lanny J.
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Subclinical phenotypes of asthma [PDF]
Current Opinion in Allergy & Clinical Immunology, 2010 Asthma is a heterogeneous disease. Identification of specific subphenotypes of asthma may further our understanding of pathophysiology and treatment response, leading to the better targeting of both existing and novel antiasthma therapies. An accurate and comprehensive clinicopathological classification system therefore remains an important priority ...
Bradding, Peter, Green, Ruth H.
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Frontiers in Veterinary Science, 2019 Equine asthma syndrome (EAS) is a common problem that affects horses of any age. Severe EAS is reported to affect 10–20% of adult horses in the northern hemisphere, while mild/moderate EAS is reported to affect 60–100% of adult horses, depending on the ...
Kaori Uchiumi Davis +3 more
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Omalizumab: clinical use for the management of asthma [PDF]
, 2012 Omalizumab, a humanized monoclonal antibody that binds circulating IgE antibody, is a treatment option for patients with moderate to severe allergic asthma whose asthma is poorly controlled with inhaled corticosteroids and inhaled long-acting ß2 agonist ...
Rekha Chaudhuri +3 more
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Journal of General and Family Medicine, 2017 AbstractCurrently, categorization based on cluster analysis by objectively grasping the diversity of pathology is being conducted and the diversity of asthma is being categorized as phenotypes. Clinically, there is categorization based on aging and on allergic diathesis which is clinically useful; however, it has not, up to now, come to the point of ...
Hirose, Masahiro, Horiguchi, Takahiko
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Severe eosinophilic bronchial asthma: new therapeutic options
Медицинский совет, 2018 Eosinophilic asthma is a common phenotype of severe asthma, occurring in at least half of patients. In recent years, there have been significant changes in the approaches to the treatment of severe bronchial asthma and, above all, eosinophilic asthma ...
N. M. Nenasheva
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Asthma in childhood: a complex, heterogeneous disease [PDF]
Korean Journal of Pediatrics, 2011 Asthma in childhood is a heterogeneous disease with different phenotypes and variable clinical manifestations, which depend on the age, gender, genetic background, and environmental influences of the patients.
Hai Lee Chung
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