Results 81 to 90 of about 2,492,374 (226)

Exploring the early observations of parents supporting their children with school attendance problems (SAPs): A co‐produced study

British Educational Research Journal, EarlyView.
Abstract School Attendance Problems (SAPs) represent a significant challenge requiring early identification and intervention. Current service provision often does not recognise early indicators that parents observe, creating gaps between when initial concerns are raised and formal support is provided.
Tereza Aidonopoulou‐Read, Michelle Pyer, Beth Bodycote, Jackie Campbell, Kirsteen Pyer   +4 more
wiley   +1 more source

Genetics of onset of asthma

, 2013
Purpose of reviewMost asthma starts early in life. Defining phenotypes of asthma at this age is difficult as many preschool children have asthma-like respiratory symptoms. This review discusses progress in defining early wheezing phenotypes and describes
Koppelman, Gerard H., Koppelman, Gerard H.; id_orcid, de Jongste, Johan C., Postma, Dirkje S., Dijk, F. Nicole   +4 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Lifetime asthma incidence is related to age at onset and allergies in western Sweden

Clinical and Translational Allergy
Although asthma is more frequently diagnosed in childhood, a substantial proportion of cases manifests in adulthood. Nonetheless, few studies have comprehensively examined asthma incidence across different ages, genders, and asthma phenotypes.
Reshed Abohalaka, Selin Ercan, Lauri Lehtimäki, Linda Ekerljung, Helena Backman, Fatma Zehra Uslu, Saliha Selin Ozuygur Ermis, Madeleine Rådinger, Bright I. Nwaru, Hannu Kankaanranta   +9 more
doaj   +1 more source

Siblings With Duchenne Muscular Dystrophy: Exploring Diagnosis Age and Disease Progression in a Genetic Therapy‐Naïve Cohort

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Duchenne muscular dystrophy (DMD) is the most common pediatric muscular dystrophy. Typically, there is a ~ 2‐year delay between symptom onset and diagnosis. Limited data on outcomes in early‐diagnosed individuals have limited the understanding of the clinical impact of early diagnosis.
Vaishnavi Brahmamdam, Cuixia Tian, Niki Armstrong, Valentina Pilipenko, Lisa J. Martin, Alexander Zygmunt, Irina Rybalsky, Lisa Reebals, Chinmayee B. Nagaraj   +8 more
wiley   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai, Anton L V Avanceña, Juan P Cata, Jamie C. Barner, Sharon H. Giordano, Chanhyun Park, Hui Zhao, Kirk E. Evoy, John K. Lin, Jennifer C. Spencer, Mariana Chavez‐MacGregor, Kelly K. Hunt, Kerollos Nashat Wanis   +12 more
wiley   +1 more source

Research Update: A Systematic Review of the Relationship Between Eating Disorder Symptoms and Parental Socioeconomic Status (SES) Among Adolescents

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) have long been viewed as disorders affecting higher socioeconomic groups, yet recent evidence shows they occur across all backgrounds. This systematic review and meta‐analysis aims to evaluate the relationship between parental socioeconomic status (SES) and ED symptoms in adolescents in the general population ...
Lea Steinstad, Alice Schittek, Marcelo R. Cardona Cabrera, Nadia Micali, Nora Trompeter   +4 more
wiley   +1 more source

Validation of Parent‐Report Questionnaires for Large‐Scale Online Screening of Avoidant/Restrictive Food Intake Disorder in Children and Adolescents

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Studies assessing the validity of screening measures for avoidant/restrictive food intake disorder (ARFID) remain scarce. We evaluated the diagnostic performance and validity of an online, parent‐reported screening approach for ARFID in a population‐based sample of children.
Diana Friskson, Felicia Dahlbäck, Laila L. L. Myrberg, Liv Hog, Nadia Micali, Cynthia M. Bulik, Lisa Dinkler   +6 more
wiley   +1 more source

Gold‐Catalyzed Cyclization of Indole‐Tethered Alkynes Enabling Synthesis of Exocyclic Alkenyl Tetrahydrocarbazoles

European Journal of Organic Chemistry, EarlyView.
An efficient gold‐catalyzed intramolecular cyclization of indole‐tethered alkynes using AgNTf2 as an additive has been developed, which provides bioactive exocyclic alkenyl tetrahydrocarbazoles with up to 85% yield. Control experiments and DFT studies indicate that the reaction proceeds via a 6‐exo‐dig cyclization pathway, with gold acetylide complexes
Haibo Mei, Jingrui He, Chengting Wang, Jorge Escorihuela, Jianlin Han   +4 more
wiley   +1 more source

THE GENETIC BASIS OF PRIMARY ADULT-ONSET DYSTONIA [PDF]

, 2011
Objectives. To identify novel genetic loci associated with primary adult-onset dystonia (AOD) and assess candidate genes from the literature. Secondary aimes.
Esposito, Marcello
core   +1 more source