Results 71 to 80 of about 2,492,374 (226)

Investigating the association between obesity and asthma in 6- to 8-year-old Saudi children:a matched case-control study [PDF]

, 2014
Background:Previous studies have demonstrated an association between obesity and asthma, but there remains considerable uncertainty about whether this reflects an underlying causal relationship.Aims:To investigate the association between obesity and ...
Anandan, Chantelle, Elton, Rob, Nahhas, Mahmoud, Bhopal, Raj, Sheikh, Aziz   +4 more
core   +1 more source

Clinical Longitudinal Evaluation After Regimen Stop (CLEAR) of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Long‐term management strategies for severe chronic rhinosinusitis with nasal polyps (CRSwNP) increasingly include biologic therapy targeting Type 2 inflammation. However, data on outcomes after complete discontinuation of dupilumab following sustained disease control are scarce.
Patrick Huber, Manuel Lasch, Veronika Volgger, Clemens Stihl, Philipp Teupe, Fabienne Oettgen, Sophia Gantner, Moritz Gröger   +7 more
wiley   +1 more source

Cognitive Dysfunction in Chronic Rhinosinusitis: A Scoping Review

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Cognitive dysfunction is increasingly recognized as an extra‐nasal manifestation of chronic rhinosinusitis (CRS). This scoping review characterizes the primary evidence on cognition in adult CRS, covering measures, treatment response, and incident dementia.
Luke M. O'Neil, Hannan A Qureshi, Logan Lindemann, David J. Cvancara, Ashton E. Lehmann, Aria Jafari   +5 more
wiley   +1 more source

Distinguishing adult-onset asthma from COPD: a review and a new approach

, 2014
Michael J Abramson,1 Jennifer L Perret,2,3 Shyamali C Dharmage,2 Vanessa M McDonald,4 Christine F McDonald3 1School of Public Health and Preventive Medicine, Monash University, 2Centre for Epidemiology and Biostatistics, University of Melbourne ...
Perret JL, McDonald CF, Abramson MJ, McDonald VM, Dharmage SC   +4 more
core  

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

Annals of Neurology, EarlyView.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini, Sean J. Pittock, Laura Cacciaguerra, Howard L. Weiner, Luke A. Schwerdtfeger   +4 more
wiley   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Dietary patterns and adult asthma: population-based case-control study.

, 2010
BACKGROUND: Epidemiological studies of diet and asthma have focused on relations with intakes of individual nutrients and foods and evidence has been conflicting. Few studies have examined associations with dietary patterns.
Thompson, R L, Shaheen, S O, Bakolis, I, Shaheen, SO, Thompson, RL, Bakolis, I; id_orcid, Hooper, R   +6 more
core   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Osteopontin contributes to late-onset asthma phenotypes in adult asthma patients

Experimental and Molecular Medicine, 2020
Asthma: Inflammatory protein drives adult-onset disease Aging and viral infections in older individuals may combine to spur the release of an inflammatory protein implicated in late-onset asthma.
Hoang Kim Tu Trinh, Thuy Van Thao Nguyen, Seo-Hee Kim, Thi Bich Tra Cao, Quoc Quang Luu, Seung-Hyun Kim, Hae-Sim Park   +6 more
doaj   +1 more source

A Twin Study of Early-Childhood Asthma in Puerto Ricans [PDF]

, 2013
Background:The relative contributions of genetics and environment to asthma in Hispanics or to asthma in children younger than 3 years are not well understood.Objective:To examine the relative contributions of genetics and environment to early-childhood ...
Canino Glorisa, Judy L. Silberg (430008), Gillespie, Nathan A., Lange, Nancy E, Lasky-Su, J, Nathan A Gillespie, Supinda Bunyavanich, Canino, G, Nancy E. Lange (430010), Silberg, JL, Juan C. Celedόn (430011), Lange Nancy E., Glorisa Canino, Glorisa Canino (151346), Bunyavanich, S, Celedόn Juan C., Celedόn, Juan C, Gillespie, NA, Gillespie, Nathan A, Gillespie Nathan A., Celedn, JC, Jessica Lasky-Su, Lasky-Su Jessica, Celedόn, Juan C., Nancy E Lange, Judy L Silberg, Bunyavanich, Supinda, Bunyavanich Supinda, Lange, Nancy E., Silberg, Judy L., Silberg, Judy L, Celedon, Juan C., Juan C Celedón, Nathan A. Gillespie (430009), Lange, NE, Lasky-Su, Jessica, Jessica Lasky-Su (273842), Supinda Bunyavanich (430007), Canino, Glorisa, Silberg Judy L.   +39 more
core   +1 more source