Results 211 to 220 of about 8,262,084 (314)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Transition: The Patient in a No-Man´s Land. [PDF]

Int Braz J Urol
de Jesus LE.
europepmc   +1 more source

Supplementation of Protein at Breakfast Rather Than at Dinner and Lunch Is Effective on Skeletal Muscle Mass in Older Adults

, 2021
Hyeon‐Ki Kim, Hanako Chijiki, Mayuko Fukazawa, Jin Okubo, Mamiho Ozaki, Takuya Nanba, Seiichirou Higashi, Miho Shioyama, Masaki Takahashi, Takashi Nakaoka, Shigenobu Shibata   +10 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

'You decided I am old enough for the transition, but not old enough to have a say?': Exploring young people's, parents', and healthcare providers' views and experiences of Type 1 Diabetes paediatric to adult healthcare transition in Saudi Arabia. [PDF]

PLoS One
Aljohani N, Forbes A, Daqrashawi G, Due-Christensen M, Donetto S, Asaad M, Tsianakas V.   +6 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Establishing Normal Serum Values of Neurofilament Light Chains and Glial Fibrillary Acidic Protein Considering the Effects of Age and Other Demographic Factors in Healthy Adults [PDF]

Alexander Rodero-Romero, Enric Monreal, Raquel Sainz-Amo, José Manuel García‐Domínguez, Noelia Villarrubia, José Luís Veiga-González, José Ignacio Fernández-Velasco, Haydee Goicochea-Briceño, Fernando Rodríguez‐Jorge, Susana Sainz de la Maza, Juan Luis Chico‐García, Alfonso Muriel, Jaime Masjuán, Lucienne Costa‐Frossard, Luisa María Villar   +14 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Health-related quality of life in cancer survivors aged 65 and older: impact of diagnosis and treatment and perceived decline associated with aging. [PDF]

Support Care Cancer
Andreu Y, Picazo C, Soto-Rubio A, Gil-Julia B.   +3 more
europepmc   +1 more source

Impact of a nurse-based intervention on medication outcomes in vulnerable older adults [PDF]

, 2018
Michael A. Steinman, Marcelo Low, Ran D. Balicer, Efrat Shadmi   +3 more
openalex   +1 more source