Results 211 to 220 of about 6,215,718 (273)

Library Service Guides, 1973-1975 [PDF]

, 2020
Appalachian Adult Education Center
core   +1 more source

Appalachian Adult Basic Education Demonstration Center Publications, 1965-1980 [PDF]

, 2021
Appalachian Adult Basic Education Demonstration Center
core   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

From Stumbling Blocks to Stepping Stones: Progress in Treating Temporal Lobe Epilepsy With Stem Cell Transplantation. [PDF]

Epilepsy Curr
Naegele JR.
europepmc   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Analysis of the Microbial Community Structure of <i>Ixodes persulcatus</i> at Each Developmental Stage. [PDF]

Animals (Basel)
Liu Y, Dong X, Sun L, Cui H, Kang J, Bu N, Zhang Y, Qi Z, Li Z, Zhang Z, Zhao L.   +10 more
europepmc   +1 more source

Decoding multicellular interaction networks–a new horizon in tumor microenvironment research

Molecular Oncology, EarlyView.
Cells in the tumor microenvironment influence tumor establishment and progression through an elaborate array of cellular interactions. Integrating transcriptomic, spatial, and intercellular crosstalk data at single‐cell resolution unveil complex, functionally distinct multicellular circuits.
Roi Balaban, Merav Cohen
wiley   +1 more source

Transition experiences of young adults with perinatal HIV in the Netherlands. [PDF]

Health Care Transit
Weijsenfeld A, van der Knaap L, Sattoe J, van Staa A, Vermont C, Nellen JFJB, Pajkrt D.   +6 more
europepmc   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Forging an easier path through graduation: Improving the patient transition from paediatric to adult critical care. [PDF]

World J Crit Care Med
Warrillow S, Gelbart B, Stevens J, Baikie G, Howard ME.   +4 more
europepmc   +1 more source