Results 111 to 120 of about 658,530 (361)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

從學習者到教學者角色轉換歷程之權力分析:三位社區大學肢體運動課程講師的敘事研究 The Process of Role Change from Learner to Instructor: A Critical Narrative Research of Three Instructors from Body Movement Classes in Community Colleges

open access: yes臺灣教育社會學研究, 2012
本研究主要目的在於探究社區大學肢體運動類課程講師從「學習者」轉變成「教學者」的過程中,所依循、複製或重構的身體意象與配套自我技術論述,及其延伸出來各類社會關係和外在社會機制間存在的「知識—身體—權力」關係,以釐清肢體運動對人們身體和價值可能帶來的生產性和壓抑性。研究發現,存在社區大學、肢體運動社群、師生與同儕間的「知識—身體—權力」關係並非零合,所有課程內容、教學策略與人際模式都處在高度不確定狀態下,透過對抗與順服並存的方式體現著自由與壓抑。倘若寄望社 ...
徐敏雄 Min-Hsiung Hsu
doaj  

Effect of online food delivery service use on dietary choices among older adults [PDF]

open access: yesSHS Web of Conferences
The purpose of this paper is to explore the relationship of the use of online food delivery (OFD) services and the wait time when using OFD services with the diet of older adults.
Liu Chih-Chi, Li Ying-Ju, Lin Hung-Chou
doaj   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

CONCEPTUAL CHALLENGES IN UNDERSTANDING INNOVATIVE EDUCATION IN ORGANIZATIONAL CONTEXT

open access: yesInternational Journal of Cognitive Research in Science, Engineering and Education, 2016
The paper suggests shifts in educational thinking about adult and continuing education practices including: goal setting, nature of the learner, character of education, and its elements including the sources in the educational process, evaluation of its ...
Klarin Mikhail
doaj   +1 more source

Exploring Programmatic Issues which Affect Continuing Legal Education in Kansas [PDF]

open access: yes, 2017
This mixed methods research study identified common mandatory continuing legal education (MCLE) practices by Kansas providers and evaluated these against established adult and continuing education best ...
Fisher, Holly B, Spikes, W. Franklin
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

PRINCIPLES OF NON-FORMAL ADULT EDUCATION FROM PERSPECTIVE OF PERMANENT EDUCATION

open access: yesStudia Universitatis Moldaviae: Stiinte ale Educatiei, 2021
This article addresses the issue of the evolution of principles regarding adult learning and education as an important segment of permanent education/lifelong learning.
USM ADMIN
doaj  

Academic journals and the politics of publication in adult, continuing and lifelong education [PDF]

open access: bronze, 2016
Marcella Milana   +4 more
openalex   +1 more source

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