Results 101 to 110 of about 704,290 (266)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
YouthYouth workers within non-profit organisations in South Africa play a vital role in supporting the government’s agenda to mainstream positive youth development through the delivery of youth services.
Thulani Andrew Chauke
doaj +1 more source
Rice Consumption in the United States: Evidence from Food Consumption Surveys [PDF]
BackgroundLittle is known about rice consumption, related food intake patterns, and the nutritional contribution that rice provides in the diets of Americans.ObjectiveTo provide information about rice consumption in the United States and the diets of ...
Batres-Marquez, S. Patricia
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
The climate crisis as an impetus for learning
European Journal for Research on the Education and Learning of AdultsThis contribution examines the kinds of situations in which people begin to learn in the context of the climate crisis. This approach differs from how learning is usually debated in environmental education, which typically focuses on why adults should ...
Maria Stimm, Jörg Dinkelaker
doaj +1 more source
Lifelong professional education: philosophical and pedagogical aspects [PDF]
Неперервна освіта передбачає особистісне й професійне зростання людини упродовж життя. Науково-методичне забезпечення розв'язання різноаспектних завдань неперервної освіти потребує посилення уваги до досліджень у галузі освіти різних категорій дорослих ...
Ничкало, Нелля Григорівна
core
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
臺灣教育社會學研究, 2012 本研究主要目的在於探究社區大學肢體運動類課程講師從「學習者」轉變成「教學者」的過程中，所依循、複製或重構的身體意象與配套自我技術論述，及其延伸出來各類社會關係和外在社會機制間存在的「知識—身體—權力」關係，以釐清肢體運動對人們身體和價值可能帶來的生產性和壓抑性。研究發現，存在社區大學、肢體運動社群、師生與同儕間的「知識—身體—權力」關係並非零合，所有課程內容、教學策略與人際模式都處在高度不確定狀態下，透過對抗與順服並存的方式體現著自由與壓抑。倘若寄望社 ...
徐敏雄 Min-Hsiung Hsu
doaj
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source