Results 111 to 120 of about 704,290 (266)

Returning to Learning: Adults' Success in College Is Key to America's Future [PDF]

, 2007
Provides an overview of research on adult learners' characteristics, risk factors, and needs at four-year institutions and in for-credit and non-credit courses, and what changes institutions and governments can implement to help adult students ...
Brian Pusser, Bruce M. Gansneder, David W. Breneman, John H. Milam, John S. Levin, Kay J. Kohl, Sarah E. Turner   +6 more
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Exploring K-12 Teachers’ Definitions and Perspectives of Cybersecurity

Journal of Cybersecurity Education, Research & Practice
Because K-12 teachers have access to private educational data, they are increasingly at risk of being affected by cybersecurity threats. Examining how teachers conceptualize cybersecurity is vital so that cybersecurity training can be tailored to ...
Gina Childers, Weverton Ataide Pinheiro, Oluwatosin Daramola, C Lindsay Linsky, Bryson Payne, Jack Byers, Daniel Baker   +6 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Facilitators and barrier factors predicting the use of mobile payments by middle-aged and older adults: Social influence as the role of precursor

Acta Psychologica
This study aims to investigate both facilitators and barriers to mobile payment adoption among middle-aged and older adults using the Technology Acceptance Model (TAM) as a theoretical framework.
Ya-Ling Wang, Yen-Ju Chen, Chih-Chi Liu
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Correctional Education and Reintegration: A Qualitative Study of Young Ex-Offenders in Cape Flats

Youth
The transition from correctional service to life in the community can be very challenging for young ex-offenders because they often lack the skills and knowledge they need to function successfully in society.
Thulani Andrew Chauke
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Training Methods Research Opportunities for a Pilot Workforce in Transition: A Literature Review

Journal of Aviation/Aerospace Education & Research
Over the next 15 years, 50% of the U.S. commercial air carrier workforce will retire, making way for younger pilots from Generations Y and Z. This review identifies the emerging pilot workforce and training methods, including emerging technologies and ...
James Birdsong, Kurt L Reesman
doaj   +1 more source

The Library-Learner Dynamic in a Changing World [PDF]

, 1986
published or submitted for ...
Weingand, Darlene E.
core