Results 111 to 120 of about 107,601 (280)

Adult education and migrations: Migrants a mixed bag?

, 2020
The papers in this issue come from two international conferences organised by Policy Studies in Adult Education, a network of the European Society for the Research in the Education of Adults. One was held in Verona in 2017, another in Prague in 2019. The
Landri Paolo, Milana Marcella, De Vita Antonietta, Mohori polar Vida A   +3 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

The Meaning, Sources and Importance of History

, 2011
The Institute for Adult Education in Tanzania developed a Multimedia Strategy to assist them to achieve its Mission ‘to design and implement quality adult and continuing education and training programmes that will enable its learners to acquire knowledge

core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

How do we best regulate youth work as a profession within the social services sector in South Africa

International Journal of Adolescence and Youth
The professionalisation of youth work in South Africa has progressed through several stages, including hosting the 2nd Commonwealth Conference on Youth Work.
Thulani Andrew Chauke
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Navigating academic integrity in the age of on-demand artificial intelligence: implications for globalizing higher education at the University of Ibadan

Frontiers in Education
In the context of globalizing higher education in Nigeria, this study investigates the implications of on-demand Artificial Intelligence (AI) tools on academic integrity.
Solomon O. Ojedeji
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

從學習者到教學者角色轉換歷程之權力分析：三位社區大學肢體運動課程講師的敘事研究 The Process of Role Change from Learner to Instructor: A Critical Narrative Research of Three Instructors from Body Movement Classes in Community Colleges

臺灣教育社會學研究, 2012
本研究主要目的在於探究社區大學肢體運動類課程講師從「學習者」轉變成「教學者」的過程中，所依循、複製或重構的身體意象與配套自我技術論述，及其延伸出來各類社會關係和外在社會機制間存在的「知識—身體—權力」關係，以釐清肢體運動對人們身體和價值可能帶來的生產性和壓抑性。研究發現，存在社區大學、肢體運動社群、師生與同儕間的「知識—身體—權力」關係並非零合，所有課程內容、教學策略與人際模式都處在高度不確定狀態下，透過對抗與順服並存的方式體現著自由與壓抑。倘若寄望社 ...
徐敏雄 Min-Hsiung Hsu
doaj  

Youth Work Practice in South Africa’s Non-Profit Organisations Through the Lens of Self-Determination Theory

Youth
Youth workers within non-profit organisations in South Africa play a vital role in supporting the government’s agenda to mainstream positive youth development through the delivery of youth services.
Thulani Andrew Chauke
doaj   +1 more source