Results 81 to 90 of about 96,125 (291)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 2010 The staff of the Donaldson Brown Continuing Education Center can benefit from the study in four ways: (1) The staff can gain information about the people who attend adult education programs.
Pedigo, Elizabeth Anderson
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Understanding vulnerability and encouraging young adults to become active citizens through education: the role of adult education professionals [PDF]
, 2019 The recent debate on active citizenship and adult education has been strongly underpinned by the discussion on how active citizenship could be exercised in a way that would promote inclusion and participation.
Toiviainen, H +5 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The influence of professional development on quality teaching in Ghanaian pre-tertiary schools
Social Sciences and Humanities OpenTeacher professional development (TPD) has garnered increasing global attention and significant financial investments in recent years, yet empirical studies examining its direct influence on teaching quality remain scarce.
Inusah Salifu +3 more
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
, 2012 This article explores the issue of older adults’ access to and participation in higher education in two countries, Aotearoa New Zealand and Scotland. It discusses older adults’ engagement with regard to patterns of participation and provision, using a ...
Findsen, Brian
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Leadership in Continuing Education: Leveraging Student-Centred Narratives
, 2014 For this study, we interviewed eight Canadian and American continuing education deans and directors to explore how their personal accounts or “stories” about leadership high- light the dynamic nature of their leadership roles. This article focuses on the
Plessis, Judith, Miller, Marilyn
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Accountability practices in adult education: Insights from actor-network theory
, 2010 Accountability mechanisms in adult education, their constitution and their effects, are of increasing concern in an era threatening massive reductions to resources for adult education activity.
Fenwick, Tara
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