Results 121 to 130 of about 701,750 (333)

Correctional Education and Reintegration: A Qualitative Study of Young Ex-Offenders in Cape Flats

open access: yesYouth
The transition from correctional service to life in the community can be very challenging for young ex-offenders because they often lack the skills and knowledge they need to function successfully in society.
Thulani Andrew Chauke
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Поготовка социальных работников в системе непрерывного образования [PDF]

open access: yes, 2019
У статті розглянуто становлення системи неперервної освіти є стратегічним завданням реформування всіх освітніх систем, що послідовно визначають свої національно-специфічні особливості, в той же час орієнтуючись на базові освітні принципи.
Лях, Тетяна Леонідівна   +1 more
core  

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Adults who learn online: Exploring the online learning readiness of nontraditional undergraduate students in a Ghanaian university

open access: yesInternational Journal of Educational Research Open
Despite the growing population of non-traditional (mature) students in online learning programmes in universities across the world, less is known about the online learning readiness of this unique category of students.
David Addae, Ellen Abakah, Delali Amuzu
doaj   +1 more source

Rice Consumption in the United States: Evidence from Food Consumption Surveys [PDF]

open access: yes
BackgroundLittle is known about rice consumption, related food intake patterns, and the nutritional contribution that rice provides in the diets of Americans.ObjectiveTo provide information about rice consumption in the United States and the diets of ...
Batres-Marquez, S. Patricia
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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