Results 61 to 70 of about 107,561 (313)

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Leadless pacemaker implantation in a patient with complex congenital heart disease and limited vascular access

Indian Pacing and Electrophysiology Journal, 2016
Management of rhythm related issues might be particularly challenging in patients with congenital heart disease due to complex anatomy and restricted vascular access.
Paolo Ferrero, Michael Yeong, Emilia D'Elia, Edward Duncan, Alan Graham Stuart   +4 more
doaj   +1 more source

Incidence and predictors of left atrial appendage thrombus on transesophageal echocardiography before elective cardioversion

Scientific Reports, 2022
Guidelines recommend transesophageal echocardiography (TEE) before cardioversion in thrombogenic arrhythmias when the requirement of ≥ 3 weeks of anticoagulation is not met.
Felix K. Wegner, Robert Radke, Christian Ellermann, Julian Wolfes, Alicia J. Fischer, Helmut Baumgartner, Lars Eckardt, Gerhard-Paul Diller, Stefan Orwat   +8 more
doaj   +1 more source

COVID-19 vaccination in adults with congenital heart disease: Real-world data from an Italian tertiary centre

International Journal of Cardiology Congenital Heart Disease, 2021
Background: real-world data on COVID-19 vaccine safety, immunogenicity and acceptance in adults with congenital heart disease (ACHD) are lacking. Methods: ACHD patients who were offered COVID-19 vaccination from January to June 2021 were included.
Flavia Fusco, Giancarlo Scognamiglio, Assunta Merola, Anna Selvaggia Roma, Carmine Nicastro, Micaela Spatarella, Maurizio D'Abbraccio, Gabriella Di Mauro, Umberto Atripaldi, Lidia Atripaldi, Anna Correra, Michela Palma, Rosaria Barracano, Nunzia Borrelli, Annalisa Capuano, Berardo Sarubbi   +15 more
doaj   +1 more source

Management of Iron Overload in Infants and Toddlers With Diamond–Blackfan Anemia Syndrome: A French–Italian Study

American Journal of Hematology, EarlyView.
ABSTRACT Diamond–Blackfan Anemia Syndrome (DBAS) is a rare congenital anemia often requiring chronic red blood cell transfusions from infancy. Without appropriate chelation, iron overload develops early and may be severe; however, no data are available on chelation in patients under 3 years of age.
Francesca Torchio, Baptiste Lecalvez, Emanuela Garelli, Coralie Mallebranche, Adriana Carando, Marie‐Pierre Castex, Nathalie Garnier, Marco Zecca, Nathalie Aladjidi, Elisa Bertoni, Arthur Sterin, Maria Licciardello, Anne Sirvent, Antonella Sau, Isabelle Marie, Benedicte Bruno, Lydie M. Da Costa, Franca Fagioli, Paola Quarello, Thierry Leblanc   +19 more
wiley   +1 more source

Iron Deficiency Anemia Detection from Hematology Parameters in Adult Congenital Heart Disease Patients

, 2013
Introduction. Iron deficiency anemia is the most common single cause of anemia worldwide. The purpose of our study was to estimate the prevalence of anemia in adult congenital heart disease (ACHD) patients, compare different hematology parameters ...
Rodríguez-González, Fayna, Martínez Quintana, Efrén   +1 more
core   +1 more source

Predictors of COVID-19 outcomes in adult congenital heart disease patients — anatomy versus function

, 2022
Background: It is unclear whether patients with adult congenital heart disease (ACHD) should be considered as an increased risk population with poor outcomes when suffering from COVID-19.Aims: This study aimed to collect clinical outcome data and to ...
Kuśmierczyk-Droszcz, Beata; Department of Congenital Heart Disease, National Institute of Cardiology, Warszawa, Poland, Hoffman, Piotr; Department of Congenital Heart Disease, National Institute of Cardiology, Warszawa, Poland, Wójcik, Anna W; Department of Congenital Heart Disease, National Institute of Cardiology, Warszawa, Poland, Kumor, Magdalena; Department of Congenital Heart Disease, National Institute of Cardiology, Warszawa, Poland, Biernacka, Elżbieta K; Department of Congenital Heart Disease, National Institute of Cardiology, Warszawa, Poland, Lipczyńska, Magdalena; Department of Congenital Heart Disease, National Institute of Cardiology, Warszawa, Poland, Kowalik, Ewa; Department of Congenital Heart Disease, National Institute of Cardiology, Warszawa, Poland   +6 more
core   +1 more source

Progression, Management, and Outcome of Aortic Valve Stenosis in Systemic Sclerosis: A Case Series

Journal of Cardiovascular Development and Disease
Background: In systemic sclerosis (SSc), cardiac involvement is frequent, heterogeneous, and related to a poor prognosis. Due to a longer life expectancy, the development of degenerative aortic stenosis (AS) is not uncommon. The aim of this article is to
Andrea Vergara, Antonio Orlando, Eleonora Caiazza, Serena Vettori, Giovanna Cuomo, Paola Argiento, Emanuele Romeo, Rosa Franzese, Berardo Sarubbi, Michele D’Alto   +9 more
doaj   +1 more source

Arrhythmias in adults with congenital heart disease [PDF]

Heart, 2002
Refinement of surgical techniques for the treatment of congenital heart disease (CHD) has created a new population of young adults with heart disease. In the USA, it is estimated that there are nearly one million CHD patients, 15–20% with disease of severity to warrant surgical intervention. As surgical mortality has fallen, the number of adults living
openaire   +2 more sources

The 9th International RASopathies Symposium

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel, Lisa Schoyer, Beth Stronach, Raya Bogdanova, Anton M. Bennett, Jaishri Blakeley, Miriam Bornhorst, Tammy Bowers, Saskia M. Brachmann, Emma Burkitt‐Wright, Kathryn Chatfield, Alessandro De Luca, Khalil El‐Chammas, Abdul Elkadri, John E. Fortunato, Bruce D. Gelb, Anne Goriely, Karen Gripp, Kassidy Grover, Lindsay Homan, Kenneth A. Kern, Maija Kiuru, Charles (Chuck) Lawson, Yong‐Seok Lee, Frank McCormick, Gina Ney, Cristina Nuevo‐Tapioles, Sara Pardej, Elizabeth I. Pierpont, Julia Plank, Nancy Ratner, Katherine A. Rauen, J. Elliott Robinson, Les Rogers, Sarah E. Sheppard, Keir Shiels, David Stevenson, Dagmar Tiemens, Matthew Traylor, K. Nicole Weaver, Marielle Yohe, Tamar Green   +41 more
wiley   +1 more source