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Growth hormone dosing variables in growth hormone-deficient adults

Growth Hormone & IGF Research, 2006
The use of growth hormone (GH) replacement for GH-deficient adults is now in its 10th year of FDA-approved use in the United States; it has been used for a longer period of time in some European countries. Despite widespread experience, there is still lack of consensus regarding the best approach to GH initiation and titration in adults with growth ...
David M, Cook, Kevin C J, Yuen
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THE INFLUENCE OF GROWTH HORMONE ON SLEEP IN ADULTS WITH GROWTH HORMONE DEFICIENCY

Clinical Endocrinology, 1990
SUMMARYEight patients with isolated growth hormone deficiency(IGHD), 20–30 years old were studied with polysomnography before and after 6 months of treatment with growth hormone (GH). During GH treatment total sleep time decreased and REM sleep time increased significantly. Delta sleep time (stage 3 + 4) did not change significantly.
C, Aström, S A, Pedersen, J, Lindholm
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Body composition in growth hormone-deficient adults

The American Journal of Clinical Nutrition, 1992
Body composition in a group of growth hormone (GH)-deficient adults was compared with a control group matched for age, sex, body height, body weight, and body mass index by using bioelectrical impedance and deuterium oxide-dilution methods and hydrodensitometry.
Binnerts, A.   +5 more
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Adult Growth Hormone Deficiency

Nihon rinsho. Japanese journal of clinical medicine, 2002
Adult-onset growth hormone deficiency (GHD) is a rare disease with an exact incidence that is not currently known, but indirect estimates based on the incidence of pituitary tumors suggest an incidence of 10 people per million annually (1). Over the last decade the adverse metabolic and psychological sequelae of adult GHD have been increasingly ...
Zehra Haider, James W. Edmondson
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Growth Hormone Deficiency in Adults

Acta Paediatrica, 1989
ABSTRACTSalomon, F., Cuneo, R.C., Hesp, R. and Sönksen, P.H. (Department of Medicine, St. Thomas's Hospital, London, UK and the Radioisotopes Division, MRC Clinical Research Centre, Harrow, Middlesex, UK). Growth hormone deficiency in adults. Acta Paediatr Scand [Suppl] 356: 69, 1989.There is a lack of information on the long‐term effects of growth ...
F. SALOMON   +3 more
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Growth hormone treatment in adults with growth hormone deficiency: The transition

Journal of Endocrinological Investigation, 2011
The approval of GH treatment of adults with GH deficiency (GHD) raises issues regarding continuation of GH treatment in the GH-deficient child following achievement of near adult height. The transition period begins in late puberty and ends with full adult maturation and includes hormonal and many lifestyle changes.
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Growth Hormone Deficiency in Adults

BioDrugs, 1998
Although growth hormone has been in clinical use for almost 40 years to promote linear growth in children with growth hormone deficiency, replacement therapy in adults was previously not deemed clinically indicated. However, intensive research over the past decade has led to important advances in our medical knowledge and improvements in the care for ...
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Adult Growth Hormone Deficiency

2022
Abstract The best-known effect of growth hormone (GH) is stimulation of longitudinal growth in children, but GH hormone secretion continues in adulthood and exerts well-characterized metabolic effects. Growth hormone deficiency in adult hypopituitary patients (GHDA) is associated with excess morbidity and mortality from cardiovascular ...
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Growth hormone deficiency in adults

Przeglad lekarski, 2008
Growth hormone (GH) deficiency in adults has only recently been recognised as a clinically important syndrome which is associated with increased morbidity and probably also with increased mortality. Its presence leads to many unfavourable changes in body composition (increased fat mass and decreased lean mass), lipid metabolism, bone mass and may ...
Robert, Krysiak, Bogusław, Okopień
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Growth Hormone Therapy in Adults with Growth Hormone Deficiency

Acta Paediatrica, 1991
P H, Sönksen   +9 more
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