Results 21 to 30 of about 110,453 (370)

The Small World of Adult Hippocampal Neurogenesis [PDF]

Frontiers in Neuroscience, 2018
Making mechanistic sense of genetically complex biological systems such as adult hippocampal neurogenesis poses conceptual and many practical challenges.
Rupert W. Overall, Rupert W. Overall, Gerd Kempermann, Gerd Kempermann   +3 more
doaj   +4 more sources

Accumulation of GSK-3β in Interneurons Impairs Adult Hippocampal Neurogenesis by Inhibiting GABAergic Transmission. [PDF]

Aging Cell
Liu F, Cui JJ, Li XL, Zhang ZM, Liang SH, Sun Y, Li JM, Qu HL, Ye J, Guo QP, Zheng Q, Liu YF.   +11 more
europepmc   +3 more sources

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis [PDF]

Cell Stem Cell, 2010
Amanda Sierra, Juan Manuel Encinas, Juan J. P. Deudero, Jessica H. Chancey, Grigori Enikolopov, Linda Overstreet‐Wadiche, Stella E. Tsirka, Mirjana Maletić‐Savatić   +7 more
openalex   +2 more sources

Hyperactive neuronal autophagy depletes BDNF and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression

Theranostics, 2023
Background: Depression is a mental disorder that poses a serious threat to human health. Adult hippocampal neurogenesis (AHN) is closely associated with the efficacy of antidepressants.
Kuo Zhang, Fan Wang, Mengying Zhai, Meiyao He, Yuxuan Hu, Li‑Guang Feng, Yuting Li, Jingyu Yang, Chun-Hui Wu   +8 more
semanticscholar   +1 more source

Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior

Nature Neuroscience, 2022
Adult hippocampal neurogenesis plays a critical role in memory and emotion processing, and this process is dynamically regulated by neural circuit activity.
Yadong Li, Yanjia Luo, Ze-Ka Chen, L. Quintanilla, Y. Chérasse, Libo Zhang, M. Lazarus, Zhi-Li Huang, Juan Song   +8 more
semanticscholar   +1 more source

Impact of neurodegenerative diseases on human adult hippocampal neurogenesis

Science, 2021
Description Disease and hippocampal disfunction Impaired function of the brain’s hippocampus can underpin psychiatric symptoms and cognitive impairment.
J. Terreros-Roncal, E. P. Moreno-Jiménez, M. Flor-García, C. B. Rodríguez-Moreno, M. Trinchero, F. Cafini, A. Rábano, M. Llorens-Martín   +7 more
semanticscholar   +1 more source

Strength exercise weakens aerobic exercise-induced cognitive improvements in rats. [PDF]

PLoS ONE, 2018
Aerobic exercise improves cognitive function and adult hippocampal neurogenesis. However, the effects of aerobic exercise combined with strength exercise on cognitive function and adult hippocampal neurogenesis are still unknown.
Yongsheng Lan, Zhaoyuan Huang, Yanjie Jiang, Xuehua Zhou, Jingyu Zhang, Dianyu Zhang, Bo Wang, Guangqing Hou   +7 more
doaj   +1 more source

Impact of pediatric traumatic brain injury on hippocampal neurogenesis

Neural Regeneration Research, 2021
Traumatic brain injury (TBI) is a major cause of mortality and morbidity in the pediatric population. With advances in medical care, the mortality rate of pediatric TBI has declined.
Mariam Rizk, Justin Vu, Zhi Zhang
doaj   +1 more source

Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine beta-hydroxylase deficient mice

IBRO Neuroscience Reports, 2022
Norepinephrine (NE), and specific adrenoceptors, have been reported to influence distinct aspects of adult hippocampal neurogenesis, including latent stem cell activation, progenitor proliferation, and differentiation.
Darshana Kapri, Krishna C. Vadodaria, Karen S. Rommelfanger, Yvonne E. Ogbonmwan, L. Cameron Liles, Kimberly A. Fernandes-Thomas, Sonali S. Salvi, Basma F.A. Husain, David Weinshenker, Vidita A. Vaidya   +9 more
doaj   +1 more source

HDAC1 Regulates Neuronal Differentiation

Frontiers in Molecular Neuroscience, 2022
In adult hippocampal neurogenesis, chromatin modification plays an important role in neural stem cell self-renewal and differentiation by regulating the expression of multiple genes. Histone deacetylases (HDACs), which remove acetyl groups from histones,
Vanesa Nieto-Estevez, Vanesa Nieto-Estevez, Gopakumar Changarathil, Gopakumar Changarathil, Adebayo Olukayode Adeyeye, Adebayo Olukayode Adeyeye, Marissa Olga Coppin, Marissa Olga Coppin, Rawan Serena Kassim, Rawan Serena Kassim, Jingfei Zhu, Jenny Hsieh, Jenny Hsieh   +12 more
doaj   +1 more source