Results 11 to 20 of about 39,669 (209)

Roles of microglia in adult hippocampal neurogenesis in depression and their therapeutics [PDF]

open access: yesFrontiers in Immunology, 2023
Adult hippocampal neurogenesis generates functional neurons from neural progenitor cells in the hippocampal dentate gyrus (DG) to complement and repair neurons and neural circuits, thus benefiting the treatment of depression.
Shaoyi Fang   +14 more
doaj   +4 more sources

Wnt signaling in the regulation of adult hippocampal neurogenesis

open access: yesFrontiers in Cellular Neuroscience, 2013
In the adult brain new neurons are continuously generated mainly in two regions, the subventricular zone of the lateral ventricles and the subgranular zone (SGZ) in the hippocampal dentate gyrus.
Lorena eVarela-Nallar   +1 more
doaj   +3 more sources

The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal neurogenesis [PDF]

open access: yesEMBO Reports
Adult neural stem cells (NSCs) in the hippocampal dentate gyrus continuously proliferate and generate new neurons throughout life. Although various functions of organelles are closely related to the regulation of adult neurogenesis, the role of ...
Naoya Murao   +7 more
doaj   +2 more sources

The role of microglia in adult hippocampus neurogenesis [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2013
Our view of microglia has dramatically changed in the last decade. From cells being silent in the healthy brain, microglia have emerged to be actively involved in several brain physiological functions, including adult hippocampal neurogenesis, cognitive
Carmelina eGemma, Adam D Bachstetter
doaj   +3 more sources

The Small World of Adult Hippocampal Neurogenesis [PDF]

open access: yesFrontiers in Neuroscience, 2018
Making mechanistic sense of genetically complex biological systems such as adult hippocampal neurogenesis poses conceptual and many practical challenges.
Rupert W. Overall   +3 more
doaj   +4 more sources

Evidences for Adult Hippocampal Neurogenesis in Humans [PDF]

open access: yesThe Journal of Neuroscience, 2021
The rodent hippocampus generates new neurons throughout life. This process, named adult hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the brains of numerous mammalian species. Direct evidence of adult neurogenesis in humans has remained elusive, although the occurrence of this phenomenon in the human dentate ...
Elena P. Moreno-Jiménez   +4 more
openaire   +3 more sources

Extent and activity of adult hippocampal neurogenesis. [PDF]

open access: yesFront Neurosci
Our understanding of adult neurogenesis has advanced far since Joseph Altman reported newborn neurons in the adult rodent brain over 60 years ago, but only recently have we been able to directly interrogate its role in the brain. While the olfactory-associated neurogenesis seen in the subventricular zone of many other mammals is greatly diminished in ...
Betters RK   +3 more
europepmc   +3 more sources

Strength exercise weakens aerobic exercise-induced cognitive improvements in rats. [PDF]

open access: yesPLoS ONE, 2018
Aerobic exercise improves cognitive function and adult hippocampal neurogenesis. However, the effects of aerobic exercise combined with strength exercise on cognitive function and adult hippocampal neurogenesis are still unknown.
Yongsheng Lan   +7 more
doaj   +1 more source

Impact of pediatric traumatic brain injury on hippocampal neurogenesis

open access: yesNeural Regeneration Research, 2021
Traumatic brain injury (TBI) is a major cause of mortality and morbidity in the pediatric population. With advances in medical care, the mortality rate of pediatric TBI has declined.
Mariam Rizk, Justin Vu, Zhi Zhang
doaj   +1 more source

Tau Protein and Adult Hippocampal Neurogenesis [PDF]

open access: yesFrontiers in Neuroscience, 2012
Tau protein is a microtubule-associated protein found in the axonal compartment that stabilizes neuronal microtubules under normal physiological conditions. Tau metabolism has attracted much attention because of its role in neurodegenerative disorders called tauopathies, mainly Alzheimer disease.
Almudena eFuster-Matanzo   +9 more
openaire   +5 more sources

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