Results 51 to 60 of about 1,839,119 (305)
F1000ResearchGeneral overview of artificial intelligence (AI) designed for academic students, workers, researchers, and teachers. A less technical introduction for those not familiar with computer science.
Hung H.V. Nguyen, Nate Breznau
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Zeitschrift für Weiterbildungsforschung - Report, 2020 Recent years have witnessed an increasing scholarly interest in the study of education, training, and skill formation from a comparative political economy perspective.
Richard Desjardins, Alexandra Ioannidou
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A framework for developing and implementing an online learning community [PDF]
, 2011 Developing online learning communities is a promising pedagogical approach in online learning contexts for adult tertiary learners, but it is no easy task.
Cowie, Bronwen, Khoo, Elaine G.L.
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
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The potential of statistical matching for the analysis of wider benefits of learning in later life
European Journal for Research on the Education and Learning of Adults, 2019 It is challenging to investigate wider benefits of adult learning, especially in later life, due to limited data on educational activities and non-monetary returns in large, longitudinal surveys.
Madlain Hoffmann +6 more
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Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Adult learning theories and medical education : a review [PDF]
, 2009 Adult learning theories describe ways in which adults assimilate knowledge, skills and attitudes. One popular theory is andragogy. This is analysed in detail in this review. The importance of extrinsic motivation and reflective practice in adult learning
Abela, Jurgen C.
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
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Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
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FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
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