Results 91 to 100 of about 348,931 (312)

Ablating adult neurogenesis in the rat has no effect on spatial processing: evidence from a novel pharmacogenetic model.

PLoS Genetics, 2013
The function of adult neurogenesis in the rodent brain remains unclear. Ablation of adult born neurons has yielded conflicting results about emotional and cognitive impairments. One hypothesis is that adult neurogenesis in the hippocampus enables spatial
James O Groves, Isla Leslie, Guo-Jen Huang, Stephen B McHugh, Amy Taylor, Richard Mott, Marcus Munafò, David M Bannerman, Jonathan Flint   +8 more
doaj   +1 more source

Female rats are resilient to the behavioral effects of maternal separation stress and exhibit stress-induced neurogenesis

Heliyon, 2020
Early-life stress causes anxiogenesis and sensitivity of stress endocrine axis, facilitated by changes in the basolateral amygdala and hippocampal neurogenesis.
Yan Jun Lee, Amelia S. Koe, Archana Ashokan, Rupshi Mitra   +3 more
doaj   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Effects of Early-Life Stress on Social and Anxiety-Like Behaviors in Adult Mice: Sex-Specific Effects

Behavioural Neurology, 2018
Stressful events in an early postnatal period have critical implications for the individual’s life and can increase later risk for psychiatric disorders.
Natalya P. Bondar, Arina A. Lepeshko, Vasiliy V. Reshetnikov   +2 more
doaj   +1 more source

Soft Ionic and Electronic Triboelectric Nanogenerators: Toward Attachable and Implantable Biomedical Applications

Advanced Materials, EarlyView.
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi, Jimin Park, Won Jun Song, Soohwan An, Seonggyu Choe, Byeong‐Rak Keum, Min Young Kim, Dae Hee Hwang, Young‐Geun Park, Sung‐Won Kim, Sangyul Baik, Gwang‐Bum Im, Younghoon Lee   +12 more
wiley   +1 more source

Examination of the relationship between attachment styles, separation anxiety and rejection sensitivity in social anxiety disorder

Medicine Science
Social anxiety disorder is a significant mental health illness that causes marked functional impairment. This study hypothesizes that rejection sensitivity, insecure attachment, and separation anxiety will be higher in people with social anxiety disorder
Fatma Gul Helvaci Celik, Meltem Pusuroglu, Mehmet Baltacioglu, Cicek Hocaoglu, Bulent Bahceci   +4 more
doaj   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

[Examination of Adult Separation Anxiety and Bonding Styles in Patients with Panic Disorder Who Applied to a Psychiatric Clinic].

Turk psikiyatri dergisi = Turkish journal of psychiatry, 2018
INTRODUCTION The attachment processes give us a theoretical frame work to understand the psychopathological development. Unsafe attachment type is often associated with the emergence of psychopathology in the later periods of life.
Ayşe Selbes, T. Berkol, Sevilay Kunt, C. Uğurpala, M. Mehtar, Pınar Gökçeimam   +5 more
semanticscholar   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Mediation of Separation Anxiety in Psychological Distress and Insomnia in Parents Who Do Not Get Child Custody Due to Divorce

Bisma The Journal of Counseling
The divorce phenomenon often poses psychological problems for both the children and the parents. Most scientific studies are more focused on the impact of the divorces merely from the children’s side, not on the impact of divorce experienced by par-ents.
Tsania Marwa, Monty. P. Satiadarma, Roswiyani   +2 more
doaj   +1 more source