Results 91 to 100 of about 3,058,602 (268)

The Association of Dysfunctional Attitudes and Adult Separation Anxiety in Pregnancy: A Cross-Sectional Study. [PDF]

Cureus, 2023
Akkus M, Akkuş F.
europepmc   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Risk Factors for Love Addiction in a Sample of Young Adult Students: A Multiple Mediation Model Exploring the Role of Adult Attachment, Separation Anxiety, and Defense Mechanisms

Behavioral Sciences
In certain situations, romantic engagement with a partner can have detrimental effects on an individual’s well-being and overall health, exhibiting features attributable to addictive behaviors. Considering the clinical significance of this phenomenon and
Eleonora Topino, Marco Cacioppo, Shady Dell’Amico, Alessio Gori   +3 more
doaj   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Is adult separation anxiety associated with offspring risk for internalizing psychiatric problems? [PDF]

Psychol Med, 2023
Finsaas MC, Klein DN.
europepmc   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Psychological screening of adults and young people following the Manchester Arena incident

BJPsych Open, 2019
BackgroundTerrorist attacks have increased globally since the late 1990s with clear evidence of psychological distress across both adults and children and young people (CYP). After the Manchester Arena terrorist attack, the Resilience Hub was established
Paul French, Alan Barrett, Kate Allsopp, Richard Williams, Chris R. Brewin, Daniel Hind, Rebecca Sutton, John Stancombe, Prathiba Chitsabesan   +8 more
doaj   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Adult separation anxiety: Personality characteristics of a neglected clinical syndrome. [PDF]

J Abnorm Psychol, 2021
Finsaas MC, Klein DN.
europepmc   +1 more source

Understanding Adult Separation Anxiety: Exploring Predictors and Comparisons with Depression, Anxiety, Intolerance of Uncertainty and Emotional Regulation in Emerging Adults

reservedIn this study, our focus is on Adult Separation Anxiety, particularly within a sample of Emerging Adults, spanning from 18 to 26 years old (72.6% women, 26.8% men). Emerging Adulthood denotes a life stage bridging adulthood and adolescence. Given
GUARATO, MARTA
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