Results 111 to 120 of about 5,977,231 (321)

Body-mass index and mortality in a prospective cohort of U.S. adults.

open access: yesNew England Journal of Medicine, 1999
BACKGROUND Body-mass index (the weight in kilograms divided by the square of the height in meters) is known to be associated with overall mortality. We investigated the effects of age, race, sex, smoking status, and history of disease on the relation ...
E. Calle   +4 more
semanticscholar   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Identifying Risk Factors of Patients with Ulcerative Colitis

open access: yesKufa Journal for Nursing Sciences
Background׃ Ulcerative colitis a lifelong inflammatory illness is marked by persistent inflammation of the mucosal surface that begins in the rectum and spreads toward the influence of a portion or the entire colon, the disease has different periods ...
Ramlah M. M. Al karaawi   +1 more
doaj   +1 more source

An association of vertebral breast cancer metastasis and multiple myeloma, revealed by a spinal cord compression

open access: yesThe Pan African Medical Journal, 2014
Authors describe the case of a patient with breast cancer and multiple myeloma as the second metachronous disease responsible for spinal cord compression.
Abdelhakim Kherfani   +5 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Assessment of Nurses' Perception toward Application of Evidence Based Practice Approach

open access: yesKufa Journal for Nursing Sciences
Background Evidence-based nursing practice (EBNP) has become one of the most effective methods for improving patient outcomes and the quality of care as well as delivering cost-efficient health care.
Nour Al-huda Muhannad Mousa   +1 more
doaj   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Successful Outcome of Chronic Intrahepatic Cholestasis in an Adult Patient with Sickle Cell/β+ Thalassemia

open access: yesCase Reports in Hematology, 2014
Sickle cell/β+ thalassemia (Hb S/β+thal) is considered as a variant form of sickle cell disease. Acute episodes of vasoocclusive pain crisis are characteristic for sickle cell disorders and may be complicated by an acute or chronic life-threatening organ
Efthymia Vlachaki   +6 more
doaj   +1 more source

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