Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Experiences of Older Adults with Frailty Not Completing an Advance Directive: A Qualitative Study of ACP Conversations. [PDF]
Wan Z +5 more
europepmc +1 more source
Issues surrounding end-of-life decision-making
Vickram Tejwani,1,* YiFan Wu,1,* Sabrina Serrano,2 Luis Segura,2 Michael Bannon,3 Qi Qian1 1Department of Medicine, Division of Nephrology and Hypertension, 2Mayo Graduate School, 3Department of Trauma, Critical Care, and General Surgery, Mayo Clinic ...
Tejwani V +5 more
doaj
Perspectives of psychiatrists on Mental Health Care Act, 2017: An in-depth pilot survey
Background: The Mental Health Care Act, 2017 (MHCA, 17) was passed through both houses of the parliament. The Indian Psychiatric Society through its Patient’s Rights Task Force committee has been deliberating various rounds of discussion at levels of ...
Astha, Shruti Srivastava, Indira Sharma
doaj +1 more source
The Law and Practice of Advance Directives and End-of-Life Care in Malaysia [PDF]
Sharon Kaur +3 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Advance Directive Completion Among Black Adults Within a Community-Based Integrated Health Care System. [PDF]
Himmelstein J +7 more
europepmc +1 more source
Erratum: Corrigendum: Advance directives and knowledge of future selves [PDF]
Christopher Buford
openalex +1 more source
The Influence of Good Death Awareness and Knowledge of Advance Directives on Attitude toward Advance Directives in Middle-Aged Adults [PDF]
Eun-Yi Yeom
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

