Results 111 to 120 of about 21,001 (290)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Experiences of Older Adults with Frailty Not Completing an Advance Directive: A Qualitative Study of ACP Conversations. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Wan Z   +5 more
europepmc   +1 more source

Issues surrounding end-of-life decision-making

open access: yesPatient Preference and Adherence, 2013
Vickram Tejwani,1,* YiFan Wu,1,* Sabrina Serrano,2 Luis Segura,2 Michael Bannon,3 Qi Qian1 1Department of Medicine, Division of Nephrology and Hypertension, 2Mayo Graduate School, 3Department of Trauma, Critical Care, and General Surgery, Mayo Clinic ...
Tejwani V   +5 more
doaj  

Perspectives of psychiatrists on Mental Health Care Act, 2017: An in-depth pilot survey

open access: yesIndustrial Psychiatry Journal
Background: The Mental Health Care Act, 2017 (MHCA, 17) was passed through both houses of the parliament. The Indian Psychiatric Society through its Patient’s Rights Task Force committee has been deliberating various rounds of discussion at levels of ...
Astha, Shruti Srivastava, Indira Sharma
doaj   +1 more source

The Law and Practice of Advance Directives and End-of-Life Care in Malaysia [PDF]

open access: hybrid, 2023
Sharon Kaur   +3 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Advance Directive Completion Among Black Adults Within a Community-Based Integrated Health Care System. [PDF]

open access: yesPerm J, 2022
Himmelstein J   +7 more
europepmc   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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