Results 161 to 170 of about 21,001 (290)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Willingness to develop an advance directive: perspectives of older persons at a national referral hospital in Uganda. [PDF]

BMC Med Ethics
Alupo C, Mwaka ES, Kwagala B, Ochieng J.
europepmc   +1 more source

Compliance with advance directives. Wrongful living and tort law incentives.

, 2008
Holly Fernandez Lynch, Michele Mathes, Nadia N. Sawicki   +2 more
openalex   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Enhancing Advance Directive Completion Among Older Adults in the Geriatrics Clinic in Indiana, USA: A Quality Improvement Initiative. [PDF]

Healthcare (Basel)
Guillen AGP, Recarte TA, Castillo MP, Ramirez MEZ, Mártir JFS.   +4 more
europepmc   +1 more source

The Effect of Health Literacy on a Brief Intervention to Improve Advance Directive Completion: A Randomized Controlled Study. [PDF]

J Prim Care Community Health, 2021
Barker PC, Holland NP, Shore O, Cook RL, Zhang Y, Warring CD, Hagen MG.   +6 more
europepmc   +1 more source

OP20 Doctors’ perspectives on adhering to advance care directives when making medical decisions for patients with chronic disease:an australian interview study [PDF]

, 2019
Karen Detering, Nadia Moore, Tessa Li Xiang Low, Linda Nolte, Marcus Sellars   +4 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Factors Associated with Family Caregivers' Intentions to Complete an Advance Directive for Individuals with Dementia: A Cross-Sectional Descriptive Study. [PDF]

Healthcare (Basel)
Park H, Kang S, Kim Y.
europepmc   +1 more source

Advance Directives and End-of-Life Care among Nursing Home Residents Receiving Maintenance Dialysis

, 2017
Manjula Kurella Tamura, Maria E. Montez‐Rath, Yoshio N. Hall, Ronit Katz, Ann M. O’Hare   +4 more
openalex   +1 more source