Results 91 to 100 of about 713,855 (309)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Ridding Ourselves of Noxious “Death Panel” Discourse

open access: yesVoices in Bioethics, 2014
On Friday, April 11, 2014, Senator Tom Coburn (R-OK), along with co-sponsors Senators Chris Coons (D-DE) and Richard Blumenthal (D-CT), introduced the “Medicare Choices Empowerment and Protection Act" (S.
Lillian Ringel
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Prevalence of Advance Directives and Do-Not-Resuscitate Orders in Community Nursing Facilities

open access: yes, 1994
OBJECTIVE: To determine the prevalence of advance directives and do-not-resuscitate (DNR) orders in nursing homes and to measure the effect of the Patient Self-Determination Act (PSDA) and patient characteristics on these prevalences.
Zweig, Steven, Terry, Martha
core   +1 more source

Psychiatric Advance Directives

open access: yesAJN, American Journal of Nursing, 2019
They can enhance the lives of patients with mental illness, but multiple obstacles impede their implementation.
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Dementia, Intelligence, and the Competence to Complete Advance Directives

open access: yes, 1999
At referral, a fifth of patients with dementia were competent to complete advance directives.
Jacoby, Robin, Hope, Tony, Fazel, Seena
core   +1 more source

The role of advance directives in preventing compulsory placement and coercive measures in Switzerland: a need to review present practice

open access: yesSwiss Medical Weekly
In Switzerland, where individual self-determination and self-responsibility are strong values, coercive measures are still very present in the care of individuals with mental health conditions.
Nikola Biller-Andorno, Sophie Gloeckler
doaj   +1 more source

Variables that influence the medical decision regarding Advance Directives and their impact on end-of-life care

open access: yesEinstein (São Paulo), 2019
The objective of this study was to identify the variables that influence physicians to implement Advance Directives and assess their impact on end-of-life care.
Larissa Mont’Alverne de Arruda   +3 more
doaj   +2 more sources

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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