Results 81 to 90 of about 713,855 (309)

Palliative Care professionals knowledge and attitudes regarding Advance Directives in Metropolitan Region, Chile

open access: yesRevista Colombiana de Bioética, 2018
Advance Directives are grounded on the principles of respect for autonomy and beneficence. They are recommended in order to facilitate better health decision-making at the end of life. In Chile, they are not legally recognised, and there
Mariana Dittborn Bellalta
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Prospective Study of Advance Directives for Life-Sustaining Care

open access: yes, 1991
To evaluate the effectiveness of advance directives, the authors conducted a prospective study over a two-year period in a nursing home. A group of 126 competent residents and 49 family members of incompetent residents were interviewed to determine ...
Danis, Marion
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Roles of Physicians, Attorneys, and Illness Experience in Advance Directives

open access: yes, 1999
BACKGROUND: Age, illness severity, functional status, and education are associated with advance directive completion. We examined these patient characteristics and discussions with attorneys and physicians in a predictive model for advance directive ...
Kazis, Lewis   +3 more
core   +1 more source

Identifying Providers' Attitudes Towards Advance Directives

open access: yes, 2015
The passage of the Patient Self-Determination Act of 1991 stipulates that facilities who receive Medicare and Medicaid funds provide information regarding advance directives to their patients. The Dartmouth Atlas of Health Care reported that in 2012, New
Eble, Elizabeth.
core   +1 more source

Advance care directives: Citizens, patients, doctors, institutions

open access: yesJournal of Public Health Research, 2019
Italian Law no. 219/2017 established the advance care directives (“Disposizioni anticipate di trattamento” – DAT), a legal document specifying the person’s wishes in relation to health, drawn up in case of the possible future incapacity to make informed ...
Paola Delbon   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Opening the Black Box: How Do Physicians Communicate About Advance Directives?

open access: yes, 1998
BACKGROUND: The quality of communication that leads to the completion of written advance directives may influence the usefulness of these documents, but the nature of that communication remains relatively unexplored. OBJECTIVE: To describe how physicians
Arnold, Robert M.   +3 more
core   +1 more source

Advance directives and the impact of timing

open access: yesSwiss Medical Weekly, 2014
PRINCIPLES: Advance directives are seen as an important tool for documenting the wishes of patients who are no longer competent to make decisions in regards to their medical care.
Ina Otte   +3 more
doaj   +1 more source

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