Results 101 to 110 of about 181,542 (334)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Advance Directives among Elderly Population: A Malaysian Experience
Journal of the Indian Academy of Geriatrics, 2017 Objective: As not many studies have been done on the topic of advance directives in Malaysia and it has yet to gain awareness among our population, we realised the need for a study to be done not only to delineate the prevalence and preference but also ...
T L Koh +3 more
doaj
End-of-life care and dementia [PDF]
, 2006 In the UK, research continues to confirm that people with certain chronic illnesses, such as chronic lung disease and cardiac failure, represent the ‘disadvantaged dying’ compared to those with terminal cancer.
Ballard, Clive +5 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Legal dilemmas of maternal brain death: The case of Marlise Muñoz [PDF]
Glasnik Advokatske komore Vojvodine, 2020 The subject of this article is a case that occurred in Texas in 2013, which has caused great debate between medical and legal professionals, and has stirred public concern.
Drljača Jagoda V.
doaj
Completion and Related Factors of Advance Directives in old adults [PDF]
, 2018 Myung Sook Kim +2 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
PS1-20: Understanding Patient Barriers and Preferences to Completing Advance Directives (AD) in the Primary Care Setting [PDF]
, 2014 J. Bryan Jones +5 more
openalex +1 more source
Virginia POST: Improving Patient- Physician Communication about End of Life Care [PDF]
, 2013 Educational Objectives 1. Examine the complexities of medical decision-making at the end of life and the inadequacy of advance directives alone to affect care at the end of life. 2.
Pile, Chris, Pole, Laura
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source