Results 111 to 120 of about 1,191,211 (370)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Advance healthcare directives: The emerging global trends and shari’ah perspectives [PDF]

open access: yes, 2017
Advance Healthcare Directives emerged due to the enhancement of patient autonomy which ideals have been firmly embedded in the development of modern medical decision making. An advance healthcare directive is a document that seeks to preserve the patient’
Alias, Fadhlina   +1 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Advance directives: cancer patients' preferences and family-based decision making

open access: yesOncoTarget, 2017
Background Advance directives are a sensitive issue among traditional Chinese people, who usually refrain from mentioning this topic until it is imperative.
Yan-Fang Xing   +9 more
semanticscholar   +1 more source

Advance Directives among Elderly Population: A Malaysian Experience

open access: yesJournal of the Indian Academy of Geriatrics, 2017
Objective: As not many studies have been done on the topic of advance directives in Malaysia and it has yet to gain awareness among our population, we realised the need for a study to be done not only to delineate the prevalence and preference but also ...
T L Koh   +3 more
doaj  

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

A Snapshot of Advance Directives in Long-Term Care: How Often Is "Do Not" Done?

open access: yesHealthcare Quarterly, 2017
Advance directives allow individuals and their families or legal guardians to communicate preferences for interventions and treatments in the event that these individuals are no longer able to make decisions for themselves.
Sheril Perry, Christina Lawand
semanticscholar   +1 more source

Palliative and End-of-Life Care for Medical Residents (Out of Print)

open access: yesMedEdPORTAL, 2007
Introduction Good care of patients at end-of-life can result in a meaningful period of personal growth for the patient and family, and a rewarding experience for the physician. While palliative care education in medical schools has improved over the past
Douglas Ross, Susan Wolfsthal
doaj   +1 more source

Advance Directives and Dementia [PDF]

open access: yesHastings Center Report, 2018
AbstractA competent person can avoid the onset of dementia by refusing life‐sustaining medical care and by voluntarily stopping eating and drinking, bringing life to an end well before any health crisis. A competent person can also try to limit the duration of dementia by drafting an advance directive that sets bounds on the life‐sustaining care ...
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

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