Results 1 to 10 of about 49,140 (359)

A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. [PDF]

PLoS ONE, 2018
Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function.
Ulrika Wendel, Nina Persson, Christian Risinger, Eva Bengtsson, Björn Nodin, Lena Danielsson, Charlotte Welinder, Gunilla Nordin Fredrikson, Bo Jansson, Ola Blixt   +9 more
doaj   +6 more sources

Fingertip-Measured Skin Carotenoids and Advanced Glycation End Product Levels in Glaucoma [PDF]

Antioxidants, 2022
Carotenoids have antioxidant properties, and the accumulation of advanced glycation end products (AGEs) is associated with reactive oxygen species production; they have attracted attention as factors predictive of the onset and progression in glaucoma ...
Yoichi Kadoh, Yuji Takayanagi, Junichi Sasaki, Masaki Tanito   +3 more
doaj   +2 more sources

Dietary galactose exacerbates autoimmune neuroinflammation via advanced glycation end product-mediated neurodegeneration [PDF]

Frontiers in Immunology
BackgroundRecent studies provide increasing evidence for a relevant role of lifestyle factors including diet in the pathogenesis of neuroinflammatory diseases such as multiple sclerosis (MS).
Stefanie Haase, Kristina Kuhbandner, Florian Mühleck, Barbara Gisevius, David Freudenstein, Sarah Hirschberg, De-Hyung Lee, Stefanie Kuerten, Ralf Gold, Aiden Haghikia, Ralf A. Linker   +10 more
doaj   +2 more sources

Advanced glycated end-products modified transferrin mediates oxidative stress and ferroptosis in podocytes via advanced glycation end-product receptor in vitro [PDF]

Scientific Reports
Previous studies have found the increased levels of transferrin (Tf) modified by advanced-glycation-end-products (AGE-Tf) in the serum of patients with type 2 diabetes mellitus and the kidneys of diabetic rats.
Pingping Zhao, Binjing Pan, Jie Gao, Xiaoyu Lv, Yirong Wang, Jingfang Liu   +5 more
doaj   +2 more sources

Anti-inflammaging effects of vitamin D in human gingival fibroblasts with advanced glycation end product stimulation [PDF]

Journal of Dental Sciences, 2023
Background/purpose: :Both periodontal disease and diabetes mellitus (DM) are long-term inflammatory disorders that are highly prevalent and have a significant health impact.
Hung-Chieh Lu, Taichen Lin, Min Yee Ng, Chang-Wei Hsieh, Yi-Wen Liao, Chun-Cheng Chen, Cheng-Chia Yu, Chun-Jung Chen   +7 more
doaj   +2 more sources

Advanced glycation end-product crosslinking activates a type VI secretion system phospholipase effector protein [PDF]

Nature Communications
Advanced glycation end-products (AGE) are a pervasive form of protein damage implicated in the pathogenesis of neurodegenerative disease, atherosclerosis and diabetes mellitus.
Steven J. Jensen, Bonnie J. Cuthbert, Fernando Garza-Sánchez, Colette C. Helou, Rodger de Miranda, Celia W. Goulding, Christopher S. Hayes   +6 more
doaj   +2 more sources

Advanced Glycation End-Product-Modified Heat Shock Protein 90 May Be Associated with Urinary Stones [PDF]

Diseases
Background: Urinary stones (urolithiasis) have been categorized as kidney stones (renal calculus), ureteric stones (ureteral calculus and ureterolith), bladder stones (bladder calculus), and urethral stones (urethral calculus); however, the mechanisms ...
Takanobu Takata, Shinya Inoue, Kenshiro Kunii, Togen Masauji, Junji Moriya, Yoshiharu Motoo, Katsuhito Miyazawa   +6 more
doaj   +2 more sources

Predictive ability of serum advanced glycation end products at 11 to 13 weeks of gestation for early-onset preeclampsiaAJOG Global Reports at a Glance

AJOG Global Reports, 2022
BACKGROUND: Placental hypoxia and resultant oxidative stress have been associated with the development of preeclampsia. Oxidative stress promotes the formation of advanced glycation end products. OBJECTIVE: This study aimed to assess whether serum levels
Minako Goto, MD, Sho-ichi Yamagishi, MD, Takanori Matsui, PhD, Keiko Koide, MD, Hiroko Takita, MD, Mayumi Tokunaka, MD, Akihiko Sekizawa, MD   +6 more
doaj   +1 more source

Biophysical Characterisation of Amadori Modified Human Serum Albumin: A Prognostic Biomarker for Diabetic Complications [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Glycation of biological macromolecules particularly protein leads to the generation of early and Advanced Glycation End (AGE) products. The interest in early glycation of protein is driven due to the fact of Amadori modified proteins having
Binish Arif, Zubair Ahmad, Gulzar Ahmad Bhat, Syed Mudassar, Khursheed Aalam   +4 more
doaj   +1 more source

Advanced glycation end products and cognitive impairment in schizophrenia.

PLoS ONE, 2021
Advanced glycation end products play a key role in the pathophysiology of schizophrenia. Cognitive impairment is one of the central features of schizophrenia; however, the association between advanced glycation end products and cognitive impairment ...
Akiko Kobori, Mitsuhiro Miyashita, Yasuhiro Miyano, Kazuhiro Suzuki, Kazuya Toriumi, Kazuhiro Niizato, Kenichi Oshima, Atsushi Imai, Yukihiro Nagase, Akane Yoshikawa, Yasue Horiuchi, Syudo Yamasaki, Atsushi Nishida, Satoshi Usami, Shunya Takizawa, Masanari Itokawa, Heii Arai, Makoto Arai   +17 more
doaj   +1 more source