Results 271 to 280 of about 49,140 (359)

Are There Differences in Skin Autofluorescence-Measured Advanced Glycation End-Product Levels between Chronic Kidney Disease and Kidney Transplant Recipients? [PDF]

Diagnostics (Basel)
Radić J, Vučković M, Đogaš H, Gelemanović A, Belančić A, Radić M.   +5 more
europepmc   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, Volume 13, Issue 1, 5 January 2026.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Nuclear Factor-Kappa-B Mediates the Advanced Glycation End Product-Induced Repression of Slc2a4 Gene Expression in 3T3-L1 Adipocytes. [PDF]

Int J Mol Sci
Michalani MLE, Passarelli M, Machado UF.
europepmc   +1 more source

Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives

, 2015
Mike A. Richardson, Robert E. Furlani, Brendan K. Podell, David F. Ackart, Jessica D. Haugen, Roberta J. Melander, Christian Melander, Randall J. Basaraba   +7 more
openalex   +1 more source

T1WI‐SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease

Advanced Science, Volume 13, Issue 1, 5 January 2026.
We developed a smart MRI nanoprobe targeting BACE1 and Aβ plaques. It crosses the blood‐brain barrier. Upon encountering BACE1, the probe is cleaved, enabling T1WI imaging detection. Subsequent reaction with ONOO− induces probe aggregation, enhancing magnetic susceptibility for sensitive SWI imaging of Aβ plaques.
Minghua Li, Aijun Shen, Xiaolong Gao, Chao Lin, Zongliang Huang, Qi Lv, Junjun Tang, Xiaolong Ma, Jiong Ni, Ju Tian, Jiaqi Wu, Xiaowen Xu, Wei Wang, Peijun Wang   +13 more
wiley   +1 more source

Glucoselysine, a unique advanced glycation end-product of the polyol pathway and its association with vascular complications in type 2 diabetes. [PDF]

J Biol Chem
Yamaguchi H, Matsumura T, Sugawa H, Niimi N, Sango K, Nagai R.   +5 more
europepmc   +1 more source

NOX2‐Driven Oxidative Stress Promotes EndMT and Uncouples Angiogenesis–Osteogenesis at the Bone–Implant Interface in Diabetes

Advanced Science, Volume 13, Issue 4, 19 January 2026.
NOX2‐driven oxidative stress disrupts angiogenesis–osteogenesis coupling at the diabetic bone–implant interface. Pharmacologic inhibition and endothelial‐specific NOX2 knockout restore type‐H endothelium, suppress EndMT, and improve osseointegration.
Zimei Wu, Qiaodan Hou, Yang Liu, Tingting Chen, Kunkun Yang, Luyao Li, Lin Wang   +6 more
wiley   +1 more source

Advanced glycation end product accumulation

, 2014
Sandeep K. Mallipattu, Jaime Uribarri
openalex   +1 more source

Associations between metabolic syndrome and regional brain iron depositions and cognitive function in middle‐aged and older adults: A two multinational cohort study

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The alterations of regional brain iron in patients with metabolic syndrome (Mets) and its relationship with cognitive function remain unclear. METHODS These analyses utilized data from two prospective cohorts, from the UK Biobank (UKB) (21,346 participants) and from Jinan, China (224 participants). We capitalized brain iron in the
Xinyue Zhang, Linfeng Yang, Na Wang, Yuanyuan Wang, Qihao Zhang, Zhenyu Cheng, Yiwen Chen, Pengcheng Liang, Meng Li, Lingfei Guo, Changhu Liang   +10 more
wiley   +1 more source

Advanced glycation end products consumption and the decline of functional capacity in patients with Parkinson’s disease: Cross-sectional study

Jenifer Cristina Teixeira de Almeida, Guilherme Carlos Brech, Natália Mariana Silva Luna, Rodrigo Tallada Iborra, José Maria Soares-Júnior, Edmund Chada Baracat, Julia Maria D ’Andréa Greve, Angélica Castilho Alonso, Adriana Machado-Lima   +8 more
openalex   +1 more source