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Advanced glycation end products and diabetic complications
Expert Opinion on Investigational Drugs, 2002Diabetic complications are major cause of morbidity and mortality in patients with diabetes. While the precise pathogenic mechanism(s) underlying conditions such as diabetic retinopathy, diabetic nephropathy and increased risk of atherosclerosis remain ill-defined, it is clear that hyperglycaemia is a primary factor that initiates and promotes ...
Stitt, Alan, Jenkins, A.J., Cooper, M.E.
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Advanced Glycation End Products in Renal Failure
Journal of Renal Nutrition, 2006Cellular and extracellular proteins suffer significant damage in vivo by glycation. Physiological proteolysis of proteins damaged by glycation forms glycation free adducts that are released into plasma for urinary excretion. Inefficient elimination of these free adducts in uremia leads to their accumulation.
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Diabetes and Advanced Glycation End Products
2017The reaction of sugars, such as glucose and glyceraldehyde, with amino groups of proteins and lipids is enhanced under hyperglycemic conditions. As a result, the formation and accumulation of senescent macroprotein derivatives called advanced glycation end products (AGEs) have been known to progress in diabetes.
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
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Treatment of muscle‐invasive and advanced bladder cancer in 2020
Ca-A Cancer Journal for Clinicians, 2020Vaibhav G Patel +2 more
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Advanced Glycation End Products in Diabetes
2022Jesús A. Mosquera-Sulbarán +1 more
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Hemodialysis Techniques and Advanced Glycation End Products
2000TESSITORE N. +5 more
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
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Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Ca-A Cancer Journal for Clinicians, 2020Aaron J Grossberg +2 more
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