Results 291 to 300 of about 63,117 (342)

Comparison of Free and Bound Advanced Glycation End Products (AGEs) in Food: A Review on the Possible Influence on Human Health.

Journal of Agricultural and Food Chemistry, 2019
: Debate on the hazard of advanced glycation end products (AGEs) in food has continued for many years, due to their uncertain bioavailability and ability to bind to their receptors (RAGEs) in vivo.
Di Zhao, Bulei Sheng, Yi Wu, Hao Li, Dan Xu, Y. Nian, Shengyong Mao, Chunbao Li, Xinglian Xu, G. Zhou   +9 more
semanticscholar   +1 more source

Advanced Glycation End Products and Bone Loss during Aging

Annals of the New York Academy of Sciences, 2005
Abstract: It is well known that bone mass density decreases with age. Age‐related bone mass loss is ascribed to several factors. Nonenzymatic glycation has been proposed as a new potential factor in the loss of bone during aging. In this study we evaluated the concentration of pentosidine, an advanced glycation end product, in cortical and trabecular ...
ODETTI, PATRIZIO, S. ROSSI S, MONACELLI, FIAMMETTA, A. POGGI, M. CIRNIGLIARO, M. FEDERICI, A. FEDERICI   +6 more
openaire   +4 more sources

Caffeic Acid Inhibits the Formation of Advanced Glycation End Products (AGEs) and Mitigates the AGEs‐Induced Oxidative Stress and Inflammation Reaction in Human Umbilical Vein Endothelial Cells (HUVECs)

Chemistry and Biodiversity, 2019
The advanced glycation end products (AGEs) are the compounds produced by non‐enzymatic glycation reaction of proteins and sugars, which can induce the generation of free radicals and the expression of inflammatory factors, thereby playing an important ...
Xiangyu Cao, Ying Xia, Meng Zeng, Weiyu Wang, Yin He, Jianli Liu   +5 more
semanticscholar   +1 more source

Advanced Glycation End Products (AGEs) and Diabetic Vascular Complications

Current Diabetes Reviews, 2005
Diabetic vascular complication is a leading cause of acquired blindness, end-stage renal failure, a variety of neuropathies and accelerated atherosclerosis, which could account for disabilities and high mortality rates in patients with diabetes. Chronic hyperglycemia is essentially involved in the development and progression of diabetic micro- and ...
Kazuo Nakamura, Sho-ichi Yamagishi, Tsutomu Imaizumi   +2 more
openaire   +3 more sources

Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation

2020
A range of chemically different compounds are known to inhibit the formation and accumulation of advanced glycation end products (AGEs) or disrupt associated signalling pathways. There is evidence that some of these agents can provide end-organ protection in chronic diseases including diabetes.
Karin Jandeleit-Dahm, Karly C. Sourris, Anna M.D. Watson   +2 more
openaire   +3 more sources

Advanced Glycation End Products, RAGE, and Aging

2010
The products of nonenzymatic glycation and oxidation of proteins and lipids, the advanced glycation end products (AGEs), accumulate in diverse biological settings including aging. AGEs may be generated rather quickly or over long duration as a consequence of distinct triggering mechanisms, thereby accounting for their roles in multiple settings and ...
Loredana G. Bucciarelli, Ravichandran Ramasamy, Ann Marie Schmidt, Shi Fang Yan   +3 more
openaire   +2 more sources

Advanced Glycation End Products of the Maillard Reaction and Their Relation to Aging

Gerontology, 1994
Long-term incubation of proteins with glucose leads to advanced glycation end products (AGE). Demonstration of AGE in vivo as well as determination of its main structure are crucial to elucidate its potential link to aging processes and diabetic complications.
Seikoh Horiuchi, Norie Araki
openaire   +3 more sources

Involvement of Advanced Glycation End-products (AGEs) in Alzheimers Disease

Current Alzheimer Research, 2004
The advanced stage of the glycation process (one of the post-translational modifications of proteins) leads to the formation of advanced glycation end-products (AGEs) and plays an important role in the pathogenesis of angiopathy in diabetic patients.
Masayoshi Takeuchi, Richard Bucala, Takayuki Watai, Nobuyuki Sasaki, Mina Iwaki, Takako Suzuki, Seiji Kikuchi, Sho-ichi Yamagishi   +7 more
openaire   +3 more sources

Serum advanced glycation end products (AGEs) are associated with insulin resistance

Diabetes/Metabolism Research and Reviews, 2011
AbstractBackgroundIn addition to the important role of advanced glycation end products (AGEs) in the pathogenesis of diabetic vascular complications, recent data suggest that advanced glycation end products can also impair insulin action in vitro. We have investigated whether circulating advanced glycation end products are associated with insulin ...
K. Tan, S. Shiu, Y. Wong, X. Tam
semanticscholar   +6 more sources

AGEs (Advanced Glycation End-products) in bone come of age

Bone
Advanced Glycation End-products (AGEs) are seen in long-lived proteins and were not expected to accumulate in the bone that turnovers and renews itself. Here, we provide a commentary on the contrary, highlighting the Special Issue of AGEs in Bone. An outcome of hyperglycemia and increased oxidative stress, AGEs form and accumulate by altering the bone ...
Deepak, Vashishth, Ruban, Dhaliwal, Mishaela, Rubin   +2 more
openaire   +2 more sources