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Role of Advanced Glycation End Products (AGEs) in Osteoporosis in Diabetes
Current Drug Targets, 2011Recent meta-analyses have revealed that the risk of bone fracture is increased in both type 1 and type 2 diabetic patients. Low bone mineral density (BMD) can not necessarily explain the link, because BMD is increased rather than decreased in type 2 diabetes, while it is consistently low in type 1 diabetes subjects.
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Role of Advanced Glycation End Products in Aging Collagen
Gerontology, 1998The collagen structure of young and old rats was examined using a scanning force microscope (SFM). Rat tail tendons of 8- and 24-month-old Wistar rats were frayed by two blades and examined using a Nanoscope III SFM. In the same tendons, the pentosidine concentrations, a marker of the Maillard reaction, were determined by HPLC.
P. Odetti +5 more
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[Importance of advanced glycation end products--AGE products].
Bratislavske lekarske listy, 1998Recent experimental findings suggest that free oxygen radicals and AGEs may be significantly involved in the onset and development of chronic diabetic complications and Alzheimer's disease. The presented review summarizes knowledge on structure and rise of these products in vitro and in vivo and the chemical and biological properties of advanced ...
V, Jakus, J, Cársky, M, Hrnciarová
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Advanced Glycation End Products (AGEs) in Diabetic Complications
2017Hyperglycemic condition in diabetes accelerates formation of advanced glycation end products (AGEs) that are formed as a result of series of reaction between reducing sugars and proteins. Accumulation of AGEs has been implicated in development of insulin resistance as well as in the pathogenesis of diabetic complications.
Shweta Bhat +3 more
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[Advanced glycation end products (AGEs) and renal failure].
Przeglad lekarski, 2006In the last decade a central role has been attributed to advanced glycation end products (AGE's) in the progression of accelerated atherosclerosis and progresion of chronic renal failure, especially in diabetic nephropathy. Deleterious effects of high AGE's concentration was observed mainly in diabetic hemodialyzed patients. D. M.
Robert, Kurowski, Jacek, Manitius
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Advanced glycation end products and skin ageing - A Review
FLORA AND FAUNAAdvanced glycation end products (AGEs) are compounds formed by non-enzymatic reaction between the carbonyl group of reducing sugars and amino group of proteins, nucleic acids, and lipids. They are formed in body tissues by both endogenous and exogenous ways.
Sanjenbam Kabita +4 more
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Advanced glycation end-products (AGES) and heart failure
European Journal of Heart Failure, 2007Advanced glycation end-products (AGEs) are molecules formed during a non-enzymatic reaction between proteins and sugar residues, called the Maillard reaction. AGEs accumulate in the human body with age, and accumulation is accelerated in the presence of diabetes mellitus. In patients with diabetes, AGE accumulation is associated with the development of
Hartog, Jasper W. L. +4 more
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