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Development of a Decision Model to Estimate the Outcomes of Treatment Sequences in Advanced Melanoma. [PDF]

Med Decis Making
de Groot S, Blommestein HM, Leeneman B, Uyl-de Groot CA, Haanen JBAG, Wouters MWJM, Aarts MJB, van den Berkmortel FWPJ, Blokx WAM, Boers-Sonderen MJ, van den Eertwegh AJM, de Groot JWB, Hospers GAP, Kapiteijn E, van Not OJ, van der Veldt AAM, Suijkerbuijk KPM, van Baal PHM.   +17 more
europepmc   +1 more source

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Pembrolizumab: A Review in Advanced Melanoma

Drugs, 2016
Pembrolizumab (Keytruda(®)) is a humanized monoclonal antibody against programmed death receptor-1 (PD-1), a key immunoinhibitory checkpoint protein implicated in down-regulating anti-tumour immune responses. This intravenous drug is indicated for the treatment of advanced (unresectable or metastatic) melanoma, on the basis of its clinical benefit in ...
Deeks Emma D, Emma D Deeks
exaly   +3 more sources

Biochemotherapy for advanced melanoma

Seminars in Oncology, 2002
The outcome of chemotherapy for patients with stage IV melanoma is unsatisfactory, since durable responses are rarely achieved. More experimental treatments, such as vaccine approaches, antibody treatments, and gene therapy are being developed and are of high scientific interest; however, their efficacy in advanced melanoma patients has so far been ...
Ulrich, Keilholz, Martin E, Gore
openaire   +4 more sources

THERAPEUTIC ADVANCES IN MELANOMA

Dermatologic Clinics, 2000
Therapy for melanoma continues to evolve, and with the expanding work in the basic pathophysiology, the continued development of biologic modifiers is expected. With new treatment regimens, the rate of remissions is improving for patients with metastatic disease.
J M, Pitts, M E, Maloney
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Advanced conjunctival melanoma

Canadian Journal of Ophthalmology, 2004
Conjunctival melanoma is a rare neoplasm with an aggressive behaviour characterized by a high tendency to develop recurrences and metastases. The authors describe the clinicopathological features of four Mexican patients with advanced conjunctival melanoma.Review of the cases of four patients with advanced conjunctival melanoma seen at an ...
Abelardo A, Rodríguez-Reyes, Dolores, Ríos y Valles-Valles, Sonia, Corredor-Casas, Alfredo, Gómez-Leal   +3 more
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Advances in melanoma therapy

Journal of the American Academy of Dermatology, 1998
This review discusses several advances in melanoma therapy that have recently occurred or are presently in a developmental stage. We discuss the history and present dogma regarding assessment of the regional lymph nodes and adjuvant therapy for melanoma.
T M, Johnson, A M, Yahanda, A E, Chang, D J, Fader, V K, Sondak   +4 more
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Recent Advances in Melanoma Tumorigenesis

Journal of Drugs in Dermatology, 2022
Melanoma is a tumor that continues to increase in both the number of cases presenting and mortality. Patients with disease that has spread beyond the cutaneous boundary still suffer from significant morbidity and mortality despite advances in immune therapy.
Michael, Bernhardt, Aaron, Bernhardt
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Recent Advances in the Treatment of Melanoma

New England Journal of Medicine, 2021
Advances in Melanoma Treatment The incidence of melanoma has increased, but mortality has declined with improved management.
Brendan D, Curti, Mark B, Faries
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Advances in cutaneous melanoma

Clinical and Translational Oncology, 2012
After several decades of slow progress in the field of melanoma, significant advances have been reported in recent years. These include a better understanding of the molecular biology of the tumour, a new staging classification system, insights into the patterns of relapse in early stage, and new drugs for the treatment of advanced disease.
Enrique, Espinosa, Alfonso, Berrocal, José Antonio, López Martín, María, González Cao, Pablo, Cerezuela, José Ignacio, Mayordomo, Salvador, Martín Algarra   +6 more
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Research Advances in the Treatment of Melanoma by Treat Melanoma

Current Topics in Medicinal Chemistry, 2015
Melanoma is a highly malignant tumor. Prognoses of melanoma patients are often unsatisfactory due to poor operational and chemoradiational efficacy. Recently, researches for melanoma treatment have found multipeptide vaccines a favorite and possible breakthrough as they are stable in chemical property and easy to be synthesized, have no carcinogenecity
Can, Liu, Si-Qi, He, Xiao-Qing, Chen, Hui-Qing, Xie, Yong, Chen, Rui, Liu, Ke, Cao, Jian-Da, Zhou   +7 more
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