Results 31 to 40 of about 288,435 (354)
Frontiers in Oncology, 2021 Combination immunotherapy can overcome the limited objective response rates of PD-1 blockade. Interferon alpha (IFN-α) has been proven to be effective in modulating immune responses and may enhance the clinical responses to PD-1 blockade.
Dong-Dong Jia +5 more
doaj +1 more source
Association of Baseline Serum Levels of CXCL5 With the Efficacy of Nivolumab in Advanced Melanoma
Frontiers in Medicine, 2019 Anti-programmed cell death protein 1 (PD1) antibodies are in wide use for the treatment of various cancers. PD1 antibody-based immunotherapy, co-administration of nivolumab and ipilimumab, is one of the optimal immunotherapies, especially in advanced ...
Taku Fujimura +19 more
doaj +1 more source
Frontiers in Oncology, 2023 ObjectiveTo investigate risk factors for advanced melanoma over 50 years of age and to develop and validate a new line chart and classification system.MethodsThe SEER database was screened for patients diagnosed with advanced melanoma from 2010 to 2019 ...
Qiufen Xi +5 more
doaj +1 more source
Novel nano-biosensors for life science systems and their applications in early, accurate, and non-invasive melanoma and other types of cancer detection [PDF]
, 2007 Melanoma (the 5th and 6th most common cancer in Caucasian males and females, respectively), is the most severe form of skin cancer, which is often fatal if recognized in its advanced stage.
Bockrath, Marc +2 more
core +1 more source
Frontiers in Oncology, 2023 IntroductionCombined immune checkpoint inhibition (ICI) with ipilimumab and nivolumab is a widely used treatment regimen for metastatic melanoma with non-resectable metastases.
Charlotte Nübel +4 more
doaj +1 more source
Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports [PDF]
, 2014 Ipilimumab is a monoclonal antibody that blocks cytotoxic T-lymphocyte antigen4 (CTLA-4), an inhibitory molecule typically expressed on T cells. Blockade of CTLA-4 induces an overall activation of T cells, including an immune-mediated anti-tumour ...
Brochez, Lieve +4 more
core +2 more sources
Curing advanced melanoma by 2025 [PDF]
Current Opinion in Oncology, 2015 To outline the most urgent challenges in the management of advanced melanoma.Considerable progress in targeted and immunotherapy of advanced melanoma has opened a perspective for a cure if all molecular and medical information is integrated in a rational precision treatment algorithm.Bioinformatics and system biology approaches will be needed to deal ...
Dummer, Reinhard +3 more
openaire +2 more sources
Regression of established subcutaneous B16-F10 murine melanoma tumors after gef gene therapy via the mitochondrial apoptotic pathway [PDF]
, 2010 ovel treatment modalities, including gene therapy, are needed for patients with advanced melanoma. We evaluated whether the gef gene, a suicide gene from Escherichia coli, had a significant cytotoxic impact on melanoma in vivo. First, we used a non-viral
Aranega, Antonia +8 more
core +2 more sources
Metástases cutâneas em melanoma de coróide
Revista Brasileira de Oftalmologia, 2011 Metastasis in choroidal melanoma is frequent on advanced diseases, involving mainly the liver, lungs and central nervous system. We report a case of cutaneous metastasis in choroidal melanoma because is an unusual condition, even in advanced disease.
Fabricio Lopes da Fonseca +1 more
doaj +1 more source
Indirect treatment comparison of dabrafenib plus trametinib versus vemurafenib plus cobimetinib in previously untreated metastatic melanoma patients. [PDF]
, 2017 BackgroundMetastatic melanoma is an aggressive form of skin cancer with a high mortality rate and the fastest growing global incidence rate of all malignancies.
Ahuja, Amit +4 more
core +2 more sources