Results 41 to 50 of about 184,433 (313)
Frontiers in Oncology, 2023 ObjectiveTo investigate risk factors for advanced melanoma over 50 years of age and to develop and validate a new line chart and classification system.MethodsThe SEER database was screened for patients diagnosed with advanced melanoma from 2010 to 2019 ...
Qiufen Xi +5 more
doaj +1 more source
Frontiers in Oncology, 2020 Recent development of integrative therapy against melanoma combines surgery, radiotherapy, targeted therapy, and immunotherapy; however, the clinical outcomes of advanced stage and recurrent melanoma are poor.
Yanfeng Cheng, Peng Shen
doaj +1 more source
Biology of advanced uveal melanoma and next steps for clinical therapeutics [PDF]
, 2014 Uveal melanoma is the most common intraocular malignancy although it is a rare subset of all melanomas. Uveal melanoma has distinct biology relative to cutaneous melanoma, with widely divergent patient outcomes.
Gutkind, JS +17 more
core +1 more source
Advances in the Immunobiological Therapies for Advanced Melanoma
Actas Dermo-Sifiliográficas (English Edition), 2017 Metastatic or locally advanced unresectable melanoma carries a high morbidity and mortality. However, notable advances have been made in recent years in the systemic treatment of this disease, with the appearance of targeted therapy using tyrosine kinase inhibitors that block the mitogen activated protein kinase pathway, and of modern immunotherapy ...
M C, Pérez Gago +2 more
openaire +2 more sources
Treatment reality of patients with BRAF-mutant advanced/metastatic melanoma in Switzerland in the era of choice [PDF]
, 2022 Cutaneous melanoma represents a major cause of cancer death in Europe. Without adequate therapy, the 5-year survival rate is 15–20% in distant metastatic disease.
Simon Bossart +17 more
core +1 more source
Metástases cutâneas em melanoma de coróide
Revista Brasileira de Oftalmologia, 2011 Metastasis in choroidal melanoma is frequent on advanced diseases, involving mainly the liver, lungs and central nervous system. We report a case of cutaneous metastasis in choroidal melanoma because is an unusual condition, even in advanced disease.
Fabricio Lopes da Fonseca +1 more
doaj +1 more source
Treatment of Advanced Metastatic Melanoma
Dermatology Practical & Conceptual, 2021 The introduction in clinical practice of new drug compounds both targeted therapies anti-BRAF and checkpoint inhibitors have largely improved our potential to manage advanced metastatic melanoma patients. This has led to a significant improvement in terms of response rates and particularly in the overall survival (OS).
Pietro Quaglino +5 more
openaire +3 more sources
Melanoma Management, 2018 Introduction: Immunotherapies, including checkpoint inhibitors (CIs) such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-1 (PD-1) inhibitors, are revolutionizing the treatment of advanced melanoma.
Elizabeth S Mearns +6 more
doaj +1 more source
Case Reports in Oncology, 2020 Immune checkpoint inhibitors (ICIs) significantly prolong survival in patients with metastatic melanoma but can lead to serious immune-related adverse events.
Yumi Kambayashi +5 more
doaj +1 more source
Cancer Medicine, 2023 Background In patients with advanced melanoma, immune‐checkpoint inhibitors (ICIs) represent the mainstay for first line treatment. Recently, relatlimab+nivolumab was proposed as a new combination therapy. This review was aimed at summarizing the current
Andrea Ossato +5 more
doaj +1 more source