Results 21 to 30 of about 184,433 (313)
Advances in the treatment of melanoma [PDF]
Clinical Medicine, 2012 #### Key Points Melanoma incidence and mortality are increasing Melanoma is relatively resistant to therapy with standard chemotherapeutic regimens The small molecule inhibitor vemurafenib that targets melanomas with a common and specific mutation (BRAF V600E) has shown promise in the ...
Lacy, Katie E. +2 more
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Dabrafenib plus trametinib versus nivolumab for advanced melanoma
Medwave, 2023 Introduction The incidence of cutaneous melanoma has increased worldwide over the years, and an incidence of 3 cases per 100,000 men and women is estimated in Chile.
Daniela Lahoz +2 more
doaj +1 more source
OUR EXPERIENCE WITH DACARBAZINE IN THE TREATMENT OF PATIENTS WITH INOPERABLE SKIN MELANOMA [PDF]
Journal of IMAB, 2016 Objective: The standard treatment for inoperable skin melanoma is chemotherapy. The aim of this study was to explore the efficacy and safety of therapy with dacarbazine in patients with advanced melanoma.
Deyan Davidov
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Translational Oncology, 2020 Real-world data on BRAF mutation frequency in advanced melanoma are lacking in Spain. Moreover, data available on clinicopathological profile of patients with advanced BRAF-mutant melanoma are currently limited.
Jose A. Lopez-Martin +11 more
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Remission of a Perimyocardial Melanoma Metastasis With Pembrolizumab Treatment
JACC: Case Reports, 2019 Malignant melanoma demonstrates the highest rate of cardiac metastases. The incidence of melanoma is rising. The prognosis of people with advanced melanoma is generally poor.
Frederik Uttenthal Larsen, MD +2 more
doaj +1 more source
Frontiers in Oncology, 2023 The development of immune checkpoint inhibitors has revolutionized the landscape of treatment of advanced melanoma in recent years. Based on the efficacy results of the phase III CheckMate 067 trial, nivolumab in combination with ipilimumab is one of the
Lucía Vázquez-Montero +4 more
doaj +1 more source
Advances in management of melanoma [PDF]
Australian and New Zealand Journal of Medicine, 1999 It is clear from the above that the sentinel node technique and assessment of circulating melanoma cells has provided important additional methods for staging and assessment of prognosis of patients with melanoma. Cure of the disease still depends on good quality surgery and implementation of quality control measures to ensure the adequacy of surgical ...
openaire +2 more sources
Biomedicines, 2022 Real-world evidence plays an important role in the assessment of efficacy and safety of novel therapies. The increasing use of immune checkpoint inhibitors (ICIs) in patients with advanced melanoma has led to notably improved clinical outcomes, while ...
Daniella Kuzmanovszki +13 more
doaj +1 more source
Frontiers in Oncology, 2018 Antibodies against programmed cell death protein 1, such as nivolumab and pembrolizumab, are widely used for treating various cancers, including advanced melanoma.
Taku Fujimura +21 more
doaj +1 more source
Frontiers in Medicine, 2019 Ipilimumab, in combination with nivolumab, is one of the promising drugs that enhance the anti-tumor immune response of patients with advanced melanoma. Since the co-administration of nivolumab with ipilimumab in the neoadjuvant setting expands melanoma ...
Taku Fujimura +7 more
doaj +1 more source