Results 11 to 20 of about 3,108,169 (356)

Advanced acral melanoma [PDF]

open access: yesJAAD Case Reports, 2015
In the United States, the incidence of melanoma is increasing faster than any other preventable cancer. Acral melanoma is the fourth most common type of cutaneous melanoma and is frequently diagnosed later in its course compared with melanoma in other anatomic locations. Here we describe a case of highly advanced acral melanoma.
Lambert Smith, Franki   +2 more
openaire   +2 more sources

Immunotherapy for Advanced Melanoma [PDF]

open access: yesJournal of Investigative Dermatology, 2008
Immunotherapy for melanoma has undergone significant change since the first attempts to treat patients with high dose IL-2. Herein, strategies to boost patient antitumor immunity through vaccination, treatment with agents that augment host immunity, and adoptive cell transfer will be discussed.
Fang, Lei   +2 more
openaire   +2 more sources

Recent advancements in melanoma management [PDF]

open access: yesInternal Medicine Journal, 2021
AbstractThe treatment options for patients with melanoma have expanded significantly over the past decade. In particular, the use of targeted therapy and immunotherapy has dramatically transformed the outlook for patients with advanced disease. These treatments are now being utilised as adjuvant therapy for patients with earlier stage melanoma after ...
Tharani Krishnan   +2 more
openaire   +2 more sources

Dabrafenib plus trametinib versus nivolumab for advanced melanoma

open access: yesMedwave, 2023
Introduction The incidence of cutaneous melanoma has increased worldwide over the years, and an incidence of 3 cases per 100,000 men and women is estimated in Chile.
Daniela Lahoz   +2 more
doaj   +1 more source

OUR EXPERIENCE WITH DACARBAZINE IN THE TREATMENT OF PATIENTS WITH INOPERABLE SKIN MELANOMA [PDF]

open access: yesJournal of IMAB, 2016
Objective: The standard treatment for inoperable skin melanoma is chemotherapy. The aim of this study was to explore the efficacy and safety of therapy with dacarbazine in patients with advanced melanoma.
Deyan Davidov
doaj   +1 more source

Nivolumab and Relatlimab in Patients With Advanced Melanoma That Had Progressed on Anti–Programmed Death-1/Programmed Death Ligand 1 Therapy: Results From the Phase I/IIa RELATIVITY-020 Trial

open access: yesJournal of Clinical Oncology, 2023
PURPOSE Nivolumab and relatlimab activity in advanced melanoma with prior progression on anti–programmed death-1/programmed death ligand 1 (PD-(L)1)-containing regimens is under investigation.
P. Ascierto   +21 more
semanticscholar   +1 more source

Frequency and Clinicopathological Profile Associated with Braf Mutations in Patients with Advanced Melanoma in Spain

open access: yesTranslational Oncology, 2020
Real-world data on BRAF mutation frequency in advanced melanoma are lacking in Spain. Moreover, data available on clinicopathological profile of patients with advanced BRAF-mutant melanoma are currently limited.
Jose A. Lopez-Martin   +11 more
doaj   +1 more source

Remission of a Perimyocardial Melanoma Metastasis With Pembrolizumab Treatment

open access: yesJACC: Case Reports, 2019
Malignant melanoma demonstrates the highest rate of cardiac metastases. The incidence of melanoma is rising. The prognosis of people with advanced melanoma is generally poor.
Frederik Uttenthal Larsen, MD   +2 more
doaj   +1 more source

Nivolumab plus ipilimumab in metastatic melanoma: a critical appraisal focused on specific subpopulations

open access: yesFrontiers in Oncology, 2023
The development of immune checkpoint inhibitors has revolutionized the landscape of treatment of advanced melanoma in recent years. Based on the efficacy results of the phase III CheckMate 067 trial, nivolumab in combination with ipilimumab is one of the
Lucía Vázquez-Montero   +4 more
doaj   +1 more source

Efficacy and safety of lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, in patients with advanced melanoma after progression on immune checkpoint inhibitors and targeted therapies: pooled analysis of consecutive cohorts of the C-144-01 study

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Background Patients with advanced melanoma have limited treatment options after progression on immune checkpoint inhibitors (ICI). Lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, demonstrated an investigator-assessed ...
J. Chesney   +25 more
semanticscholar   +1 more source

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