Results 11 to 20 of about 184,433 (313)
Curing advanced melanoma by 2025 [PDF]
PURPOSE OF REVIEW To outline the most urgent challenges in the management of advanced melanoma. RECENT FINDINGS Considerable progress in targeted and immunotherapy of advanced melanoma has opened a perspective for a cure if all molecular and medical information is integrated in a rational precision treatment algorithm. SUMMARY Bioinformatics and system
Dummer, Reinhard +3 more
openaire +7 more sources
New Advances in Melanoma [PDF]
Melanoma is a very aggressive tumor which is derived from the transformation of pigment-producing cells termed the melanocytes. This cancer type accounts for most of the deaths associated with skin cancer as well as its incidence and is in constant ...
core +2 more sources
Advanced melanoma is one of the deadliest cancers, owing to its invasiveness and its propensity to develop resistance to therapy. Surgery remains the first-line treatment for early-stage tumors but is often not an option for advanced-stage melanoma ...
Conor M. Prendergast +8 more
doaj +1 more source
Advances in immunotherapy for melanoma [PDF]
In recent years, the introduction and Federal Drug Administration approval of immune checkpoint inhibitor antibodies has dramatically improved the clinical outcomes for patients with advanced melanoma. These antagonist monoclonal antibodies are capable of unleashing dormant or exhausted antitumor immunity, which has led to durable complete and partial ...
Redman, Jason M. +2 more
openaire +2 more sources
Immunotherapy for Advanced Melanoma [PDF]
Immunotherapy for melanoma has undergone significant change since the first attempts to treat patients with high dose IL-2. Herein, strategies to boost patient antitumor immunity through vaccination, treatment with agents that augment host immunity, and adoptive cell transfer will be discussed.
Fang, Lei +2 more
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In the United States, the incidence of melanoma is increasing faster than any other preventable cancer. Acral melanoma is the fourth most common type of cutaneous melanoma and is frequently diagnosed later in its course compared with melanoma in other anatomic locations. Here we describe a case of highly advanced acral melanoma.
Lambert Smith, Franki +2 more
openaire +2 more sources
Treatment of Advanced Melanoma: Past, Present and Future
Therapeutic options for treating advanced melanoma are progressing rapidly. Until six years ago, the regimen for treating advanced melanoma mainly comprised cytotoxic agents such as dacarbazine, and type I interferons.
Taku Fujimura +4 more
doaj +1 more source
Adjuvant Treatments of Adult Melanoma: A Systematic Review and Network Meta-Analysis
Multiple treatments of unresectable advanced or metastatic melanoma have been licensed in the adjuvant setting, causing tremendous interest in developing neoadjuvant strategies for melanoma.
Mingyi Jing +12 more
doaj +1 more source
Advances in immunotherapy for melanoma [PDF]
Paolo A Ascierto obtained his MD from the University of Naples, Italy, where he earned board certification in oncology. He is currently Director at the Unit of Melanoma, Cancer Immunotherapy and Innovative Therapy Unit, National Tumor Institute 'Fondazione G. Pascale', Naples, Italy. Before his present position, he served consecutive positions there as
Paolo A, Ascierto, James, Larkin
openaire +2 more sources
Update on Immune Checkpoint Inhibitors for Conjunctival Melanoma
The management of conjunctival melanoma is challenging due to the more frequent local recurrence and metastasis compared to other conjunctival neoplasms.
Ho-Seok Sa, Claire Daniel, Bita Esmaeli
doaj +1 more source

