Results 31 to 40 of about 17,535 (200)
The Journal of Maternal-Fetal & Neonatal MedicineObjectives Extremes of maternal age are associated with an increased risk of adverse pregnancy outcomes (APOs). Less is known about the independent effects of extremes of paternal age on reproductive risk.Methods We conducted a secondary analysis using ...
Patrick M. Conley +3 more
doaj +1 more source
Paternal aging and increased risk of congenital disease, psychiatric disorders, and cancer
Asian Journal of Andrology, 2016 As couples are increasingly delaying parenthood, the effect of the aging men and women on reproductive outcomes has been an area of increased interest. Advanced paternal age has been shown to independently affect the entire spectrum of male fertility as ...
Simon L Conti, Michael L Eisenberg
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The Effect of Paternal Age on Fetal Birth Outcomes
American Journal of Men's Health, 2012 Research investigating the role of paternal age in adverse birth outcomes is limited. This population-based retrospective cohort study used the Missouri maternally linked data set from 1989 to 2005 to assess whether paternal age affects fetal birth ...
Amina P. Alio PhD +6 more
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Paternal age and offspring congenital heart defects: a national cohort study. [PDF]
PLoS ONE, 2015 Paternal age has been associated with offspring congenital heart defects (CHDs), which might be caused by increased mutations in the germ cell line because of cumulated cell replications. Empirical evidences, however, remain inconclusive. Furthermore, it
Xiu Juan Su +5 more
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Telomere length, family history, and paternal age in schizophrenia
Molecular Genetics & Genomic Medicine, 2014 Leukocyte telomere length (LTL) is longer in association with advanced paternal age, but this association has not been examined along with family history (FH) in schizophrenia.
Dolores Malaspina +6 more
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Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Advanced Science, EarlyView.Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Interaction between social behavior and paternal age in offspring of the same paternal mice
Neuropsychopharmacology Reports, 2022 Aim Previous studies reported that advanced paternal age (APA) may increase the risk of autism spectrum disorder (ASD) in offspring. However, effects of APA on behaviors have not been investigated in offspring of the same paternal mice. The present study
Miho Tanaka +6 more
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Advanced Science, EarlyView.An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee +11 more
wiley +1 more source
Advanced Science, EarlyView.DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng +16 more
wiley +1 more source
PLoS ONE, 2010 BackgroundRecent findings suggest advanced paternal age may be associated with impaired child outcomes, in particular, neurocognitive skills. Such patterns are worrisome given relatively universal trends in advanced countries toward delayed nuptiality ...
Ryan D Edwards, Jennifer Roff
doaj +1 more source