Results 21 to 30 of about 17,535 (200)

Paternal age predicts live birth in women above 40 years of age undergoing in-vitro fertilization (IVF)

Clinical and Experimental Obstetrics & Gynecology, 2021
Purpose: To determine which factors predict pregnancy outcome in women aged 40 years and above who underwent in-vitro fertilization. Method: We conducted a retrospective case-control study of 631 women aged 40–46 years, who underwent a total of 904 IVF ...
Guy Shrem, Nouf M. Alasmari, Jacques Balayla, Alexander Volodarsky-Perel, Weon-Young Son, Michael H. Dahan   +5 more
doaj   +1 more source

Parental age effects on neonatal white matter development

NeuroImage: Clinical, 2020
Objective: Advanced paternal age is associated with poor offspring developmental outcome. Though an increase in paternal age-related germline mutations may affect offspring white matter development, outcome differences could also be due to psychosocial ...
Oliver Gale-Grant, Daan Christiaens, Lucilio Cordero-Grande, Andrew Chew, Shona Falconer, Antonios Makropoulos, Nicholas Harper, Anthony N Price, Jana Hutter, Emer Hughes, Suresh Victor, Serena J Counsell, Daniel Rueckert, Joseph V Hajnal, A David Edwards, Jonathan O'Muircheartaigh, Dafnis Batalle   +16 more
doaj   +1 more source

Whether the Effect of Sperm DNA Fragmentation on the Clinical and Laboratory Outcomes Changes with the Paternal age in the intracytoplasmic sperm injection Cycles of Donor Oocytes

Gynecology Obstetrics & Reproductive Medicine, 2022
OBJECTIVE: The present study aimed to know the effect of paternal age together with Sperm DNA fragmentation on the clinical and laboratory outcomes in the donor oocyte intracytoplasmic sperm injection cycles.
Deepthi Repalle, saritha kv, Shilpa Bhandari, Jitendra Choudhary   +3 more
doaj   +1 more source

Advanced paternal age is associated with impaired neurocognitive outcomes during infancy and childhood. [PDF]

PLoS Medicine, 2009
BackgroundAdvanced paternal age (APA) is associated with an increased risk of neurodevelopmental disorders such as autism and schizophrenia, as well as with dyslexia and reduced intelligence.
Sukanta Saha, Adrian G Barnett, Claire Foldi, Thomas H Burne, Darryl W Eyles, Stephen L Buka, John J McGrath   +6 more
doaj   +1 more source

Have maternal or paternal ages any impact on the prenatal incidence of genomic copy number variants associated with fetal structural anomalies?

PLoS ONE, 2021
The objective of this study was to determine whether maternal or paternal ages have any impact on the prenatal incidence of genomic copy number variants (CNV) in fetuses with structural anomalies.
Marta Larroya, Marta Tortajada, Eduard Mensión, Montse Pauta, Laia Rodriguez-Revenga, Antoni Borrell   +5 more
doaj   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis. [PDF]

Adv Sci (Weinh)
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Liu Y, Liu S, Liang H, Yang J, Li Y, Yin J, Zhang X, Zhang Y, Bai D, Yan Z, Zhang Z, Jia Y, Liu K, Sheng Y, Xiang J, Xi C, Dong B, Lei X, Chen J, Wang H, Guo Y, Zhang Y, Gao S, Liu W.   +23 more
europepmc   +2 more sources

Paternal age impairs in vitro embryo and in vivo fetal development in murine

Scientific Reports, 2022
The association between advanced paternal age and impaired reproductive outcomes is still controversial. Several studies relate decrease in semen quality, impaired embryo/fetal development and offspring health to increased paternal age.
Larissa Araújo Stábile, Camilla Mota Mendes, Marcelo Demarchi Goissis, Raphaela Gabrielle Brito Sousa, Marcílio Nichi, José Antônio Visintin, Thais Rose dos Santos Hamilton, Mayra Elena Ortiz D’ Ávila Assumpção   +7 more
doaj   +1 more source

Association Between Paternal Age and Birth Weight in Preterm and Full-Term Birth: A Retrospective Study

Frontiers in Endocrinology, 2021
PurposeWhile it is well documented that maternal adverse exposures contribute to a series defects on offspring health according to the Developmental Origins of Health and Disease (DOHaD) theory, paternal evidence is still insufficient.
Yiting Mao, Yiting Mao, Chen Zhang, Chen Zhang, Yinyu Wang, Yinyu Wang, Yicong Meng, Yicong Meng, Lei Chen, Cindy-Lee Dennis, Jianzhong Sheng, Yanting Wu, Hefeng Huang, Hefeng Huang, Hefeng Huang   +14 more
doaj   +1 more source

Does Advanced Paternal Age Increase the Rate of Paternally Derived Aneuploidy as Detected by SNP Array?

Fertility & Reproduction, 2022
Objective: Recent studies have investigated the impact of paternal age on the incidence of embryo aneuploidy using young oocyte donors to control for maternal age, with conflicting results observed.
Tanya SAMARASEKERA, Tristan HARDY, Luk ROMBAUTS, Mark P. GREEN, Yanhe LIU, Deirdre ZANDER-FOX, Elissa WILLATS   +6 more
doaj   +1 more source

The Potential Relationship Between The Environmental Risk Factors And Social Cognition in Psychosis

European Psychiatry, 2022
Introduction In schizophrenia research, little is known about the relationship of environmental exposures with social cognition deficits. Objectives We aimed to investigate the relationship between social cognitive performance and well-defined ...
S. Cicek, F. Karadag
doaj   +1 more source