Results 11 to 20 of about 17,535 (200)

Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance [PDF]

Journal of Neuroinflammation
Background The trend of postponing childbearing age is prevalent worldwide. Advanced paternal age (APA) is associated with adverse pregnancy outcomes and offspring health.
Yiting Mao, Yicong Meng, Kexin Zou, Ningxin Qin, Yinyu Wang, Jing Yan, PinJia Chen, Yi Cheng, Weihui Shi, Chengliang Zhou, Huixi Chen, Jianzhong Sheng, Xinmei Liu, Jiexue Pan, Hefeng Huang   +14 more
doaj   +2 more sources

Advanced paternal age and risk of schizophrenia in offspring - Review of epidemiological findings and potential mechanisms. [PDF]

Schizophr Res, 2021
Khachadourian V, Zaks N, Lin E, Reichenberg A, Janecka M.   +4 more
europepmc   +2 more sources

Paternal age and sperm DNA fragmentation independently affect embryonic ploidy but not euploid embryo implantation potential [PDF]

Frontiers in Endocrinology
ObjectiveTo systematically evaluate the associations between paternal factors (age, semen parameters, body mass index, sperm DNA fragmentation index (DFI), and leukocyte count), embryonic ploidy, and the clinical implantation potential of euploid embryos.
Zhiming Li, Xiufeng Lin, Xubin Zhang, Xiaowu Fang, Zhanhui Ou, Junye Huo, Wanna Ke, Jiaqi Wu, Wenjuan Yu, Lan Ma, Xiaojun Wen   +10 more
doaj   +2 more sources

Pregnancy in advanced age of mothers and fathers

Акушерство, гинекология и репродукция, 2021
There is a higher incidence of infertility, chromosomal aberrations, poor results of in vitro fertilization, ectopic pregnancies, spontaneous abortion, preeclampsia, placenta previa, gestational diabetes mellitus, caesarean section, chronic diseases with
C. Dadak
doaj   +1 more source

Advanced parental age: Is it contributing to an increased incidence of non-syndromic craniosynostosis? A review of case-control studies

Journal of Oral Biology and Craniofacial Research, 2021
Background: Craniosynostosis (CS) is a congenital birth defect characterized by the premature fusion of one or several calvarial suture(s). CS could lead to serious complications, such as intracranial hypertension and neurodevelopmental impairment. There
Kenzy Abdelhamid, Rea Konci, Hassan ElHawary, Andrew Gorgy, Lee Smith   +4 more
doaj   +1 more source

Advanced paternal age does not affect embryo aneuploidy following blastocyst biopsy in egg donor cycles. [PDF]

J Assist Reprod Genet, 2019
Carrasquillo RJ, Kohn TP, Cinnioglu C, Rubio C, Simon C, Ramasamy R, Al-Asmar N.   +6 more
europepmc   +2 more sources

The role of advanced paternal age in modern reproductive medicine [PDF]

Asian Journal of Andrology, 2016
Christopher Wu, Larry I Lipshultz, Jason R Kovac   +2 more
doaj   +2 more sources

Advanced Paternal Age in Focus: Unraveling Its Influence on Assisted Reproductive Technology Outcomes. [PDF]

J Clin Med
Kaltsas A, Zikopoulos A, Vrachnis D, Skentou C, Symeonidis EN, Dimitriadis F, Stavros S, Chrisofos M, Sofikitis N, Vrachnis N, Zachariou A.   +10 more
europepmc   +2 more sources

Impact of paternal age on IVF and pregnancy outcomes with only normal sperm parameters

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: Previous reports on advanced paternal age effects on assisted reproductive technology (ART) vary considerably and those on frozen–thawed embryo transfer (FET) are rare.
Nobuyuki Kidera, Tomonori Ishikawa, Toshihiro Kawamura, Naoyuki Miyasaka   +3 more
doaj   +1 more source

Age-Dependent Alterations in Semen Parameters and Human Sperm MicroRNA Profile

Biomedicines, 2023
The trend to delay parenthood is increasing, impacting fertility and reproductive outcomes. Advanced paternal age (APA), defined as men’s age above 40 years at conception, has been linked with testicular impairment, abnormal semen parameters, and poor ...
Joana Santiago, Joana V. Silva, Manuel A. S. Santos, Margarida Fardilha   +3 more
doaj   +1 more source