Results 51 to 60 of about 3,175,008 (304)
Update on Calcium Signaling in Cystic Fibrosis Lung Disease
Frontiers in Pharmacology, 2021 Cystic fibrosis (CF) is an autosomal recessive disorder characterized by mutations in the cystic fibrosis transmembrane conductance regulator gene, which causes multifunctional defects that preferentially affect the airways.
Alessandro Rimessi +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Advancing therapy for hypercholesterolemia
Expert Opinion on Pharmacotherapy, 2010 Hypercholesterolemia holds a key role in the development and progression of atherosclerosis and is a causative factor of coronary artery disease. Current guidelines for cholesterol treatment target low-density cholesterol (LDL-C) as the primary goal of therapy.
Toutouzas, Konstantinos +3 more
openaire +3 more sources
Automation in Cell and Gene Therapy manufacturing Drivers and economy of scale
, 2023 Automation in cell and gene therapies - drivers and economy of scale: - How automation and digitalisation are relevant to up/outscaling cell and gene therapies in Europe - Different automation approaches to cell therapy ...
Herbst, Laura
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Cancer metabolism and mitochondria: Finding novel mechanisms to fight tumours
EBioMedicine, 2020 Mitochondria are dynamic organelles that have essential metabolic activity and are regarded as signalling hubs with biosynthetic, bioenergetics and signalling functions that orchestrate key biological pathways.
Sonia Missiroli +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Using evidence to improve Psychological Therapies Services [PDF]
, 2005 Psychological therapy services offer help to clients with many different sorts of mental health problems using a variety of therapies provided by a range of different professional groups and are supported by a large amount of research evidence.
Lucock, Mike +2 more
core +2 more sources
Cardiovascular UltrasoundMitral valve prolapse (MVP) is a common condition affecting approximately 3% of the population, typically with a benign clinical course. However, a small subset of patients (5–10%) may develop severe mitral regurgitation or arrhythmias, which can lead to
Francesco Fulvio Faletra +10 more
doaj +1 more source
Human Neural Stem Cells for Cell-Based Medicinal Products
Cells, 2021 Neural stem cells represent an attractive tool for the development of regenerative therapies and are being tested in clinical trials for several neurological disorders.
Beatriz Fernandez-Muñoz +3 more
doaj +1 more source