Results 51 to 60 of about 4,847,313 (302)

Is There a Risk of Lymphoma Associated With Anti-tumor Necrosis Factor Drugs in Patients With Inflammatory Bowel Disease? A Systematic Review of Observational Studies

Frontiers in Pharmacology, 2019
Background: Inflammatory bowel diseases (IBDs) are generally not considered a risk factor for the development of lymphoma. When considering IBD treatments, there is good evidence supporting thiopurines (azathioprine, 6-mercaptopurine) as a risk factor ...
Sara Ferraro, Luca Leonardi, Irma Convertino, Corrado Blandizzi, Corrado Blandizzi, Marco Tuccori, Marco Tuccori   +6 more
doaj   +1 more source

Practice, knowledge, and attitude about adverse drug reactions, adverse drug reaction reporting and pharmacovigilance among undergraduates, house surgeons, and post-graduates of a tertiary care teaching hospital in Andhra Pradesh – A cross-sectional questionnaire-based study

National Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Adverse drug reactions (ADRs) are important cause of morbidity and mortality. ADR reporting will help to identify and prevent ADR. However, lack of awareness and sensitization make it a difficult task. There is under reporting of ADR.
Suresh Malla, Venugopal Rao Tanneru, Vinutha S, Lakshmana Rao N   +3 more
doaj   +1 more source

Adverse events and adverse drug reaction in geriatrics.

, 2023
Adverse events and adverse drug reaction in geriatrics.
Yong-Geun Park (3337623), Sang Won Moon (16426060), Jong-Keun Seon (5534801), Ji Hyun Ahn (15596699), Eui Sung Choi (16426054), Joon-Ho Wang (16426051), Ki-Bong Park (16426039), Oog Jin Shon (16426045), Lih Wang (16426048), Young-Jin Seo (452424), Hyuk-Soo Han (8108729), Jeong-Ku Ha (16426057), Kang-Il Kim (8835995), Jae Gyoon Kim (16426036), Ji Hoon Bae (16426042)   +14 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

“Adverse Drug Reaction Reporting” Knowledge, Attitude and Practices of Community Pharmacy Dispensers in Dar es salaam, Tanzania [PDF]

, 2011
Under reporting of adverse drug reactions (ADRs) by healthcare personnel is a common problem of many Pharmacovigilence programs. Lack of involvement of healthcare professionals such as pharmacists and other pharmaceutical dispensers has been cited as one
Shimwela, Grace Mng’ong’o
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Cytomegalovirus infection initiates inflammatory bowel disease by activating a positive MyD88/NF-κB feedback loop in allogeneic skin transplantation mice

Virology Journal
Infection with the cytomegalovirus (CMV) is common. Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal tract. CMV infection is involved in IBD pathogenesis. The abnormal activation of myeloid differentiation
Ming-Xian Chen, Yu Chen, Rui Fu, Jie-Yi Wang, Sai-Yue Liu, Tang-Biao Shen   +5 more
doaj   +1 more source

Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury

Frontiers in Pharmacology, 2019
Acetaminophen (APAP) is a widely used over-the-counter antipyretic and analgesic drug. Overdose of APAP is the leading cause of hospital admission for acute liver failure.
Shiyun Pu, Qinhui Liu, Yanping Li, Rui Li, Tong Wu, Zijing Zhang, Cuiyuan Huang, Xuping Yang, Jinhan He, Jinhan He   +9 more
doaj   +1 more source

Adverse events and adverse drug reaction in overall population.

, 2023
Adverse events and adverse drug reaction in overall population.
Yong-Geun Park (3337623), Sang Won Moon (16426060), Jong-Keun Seon (5534801), Ji Hyun Ahn (15596699), Eui Sung Choi (16426054), Joon-Ho Wang (16426051), Ki-Bong Park (16426039), Oog Jin Shon (16426045), Lih Wang (16426048), Young-Jin Seo (452424), Hyuk-Soo Han (8108729), Jeong-Ku Ha (16426057), Kang-Il Kim (8835995), Jae Gyoon Kim (16426036), Ji Hoon Bae (16426042)   +14 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source